You are in the accessibility menu

Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/25980
Full metadata record
DC FieldValueLanguage
dc.contributor.authorSantos, Daniela Pereira dos-
dc.contributor.authorBergamini, Marcio Fernando-
dc.contributor.authorZanoni, Maria Valnice Boldrin-
dc.date.accessioned2014-05-20T14:19:53Z-
dc.date.accessioned2016-10-25T17:41:19Z-
dc.date.available2014-05-20T14:19:53Z-
dc.date.available2016-10-25T17:41:19Z-
dc.date.issued2010-10-01-
dc.identifierhttp://www.electrochemsci.org/papers/vol5/5101399.pdf-
dc.identifier.citationInternational Journal of Electrochemical Science. Belgrade: Electrochemical Science Group, v. 5, n. 10, p. 1399-1410, 2010.-
dc.identifier.issn1452-3981-
dc.identifier.urihttp://hdl.handle.net/11449/25980-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/25980-
dc.description.abstractThe poly-L-glutamic acid (PGA), was used a biodegradable polymers as conjugated to doxorubicin (DXR) and also in the modification glassy carbon electrode. The interaction operate via terminal amino groups of the drug and the side chain carboxyl groups of branched PGA film and it is the base to develop a simple voltammetric sensor for the determination of doxorubicin in human urine. The preconcentration of DXR on the modified electrode occurs under open circuit and studied by the methods of square wave voltammetry to monitor the drug. Standard curves were linear over the concentration range of 2.20 - 44.5 mu mol L(-1) giving a detection limit of 0.45 mu mol L(-1) show that the proposed sensor is suitable for doxorubicin determination in real samples.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.format.extent1399-1410-
dc.language.isoeng-
dc.publisherElectrochemical Science Group-
dc.sourceWeb of Science-
dc.subjectDoxorubicinen
dc.subjectpoly-L-glutamic aciden
dc.subjectadsorptionen
dc.subjectsemiquinone free radicalen
dc.subjecturineen
dc.titleApproach on the Electrochemical Reactivity of Poly-L-Glutamic Acid Against Doxorubicin and Its Application in the Development of a Voltammetric Sensoren
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionUniversidade Federal do Paraná (UFPR)-
dc.description.affiliationUniv São Paulo State, Inst Chem, UNESP, BR-14801970 Araraquara, SP, Brazil-
dc.description.affiliationUFPR, Ctr Politecn, Setor Ciencias Exatas, Dept Quim, BR-81531990 Curitiba, Parana, Brazil-
dc.description.affiliationUnespUniv São Paulo State, Inst Chem, UNESP, BR-14801970 Araraquara, SP, Brazil-
dc.description.sponsorshipIdFAPESP: 3/06598-3-
dc.description.sponsorshipIdFAPESP: 04/00111-8-
dc.identifier.wosWOS:000282329800001-
dc.rights.accessRightsAcesso aberto-
dc.identifier.fileWOS000282329800001.pdf-
dc.relation.ispartofInternational Journal of Electrochemical Science-
dc.identifier.orcid0000-0002-2296-1393-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

There are no files associated with this item.
 

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.