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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/26019
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dc.contributor.authorFelippe, Lidiane Gaspareto-
dc.contributor.authorBaldoqui, Debora Cristina-
dc.contributor.authorKato, Massuo Jorge-
dc.contributor.authorBolzani, Vanderlan da Silva-
dc.contributor.authorGuimaraes, Elsie Franklin-
dc.contributor.authorCicarelli, Regina Maria Barreto-
dc.contributor.authorFurlan, Maysa-
dc.date.accessioned2014-05-20T14:20:03Z-
dc.date.accessioned2016-10-25T17:41:23Z-
dc.date.available2014-05-20T14:20:03Z-
dc.date.available2016-10-25T17:41:23Z-
dc.date.issued2008-01-01-
dc.identifierhttp://dx.doi.org/10.1016/j.phytochem.2007.08.012-
dc.identifier.citationPhytochemistry. Oxford: Pergamon-Elsevier B.V. Ltd, v. 69, n. 2, p. 445-450, 2008.-
dc.identifier.issn0031-9422-
dc.identifier.urihttp://hdl.handle.net/11449/26019-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/26019-
dc.description.abstractFive tetrahydrofuran lignans and two known flavones were isolated from the aerial parts of Peperomia blanda. The structures of the isolated lignans were elucidated by interpretation of their spectroscopic data, including by gHMQC and gHMBC. The relative and absolute configurations of the isolates were determined from NOESY interactions and optical properties, respectively. Four of the lignans were diastercomeric whilst one was of mixed biosynthetic origin. All but one of the lignans exhibited high in vitro trypanocidal activity when assayed against epimastigotes of Trypanosoma cruzi strain Y. (C) 2007 Elsevier Ltd. All rights reserved.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
dc.format.extent445-450-
dc.language.isoeng-
dc.publisherPergamon-Elsevier B.V. Ltd-
dc.sourceWeb of Science-
dc.subjectPeperomia blandaen
dc.subjectPiperaceaeen
dc.subjecttetrahydrofuran lignansen
dc.subjectstructural elucidationen
dc.subjecttrypanocidal activityen
dc.titleTrypanocidal tetrahydrofuran lignans from Peperomia blandaen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionUniversidade de São Paulo (USP)-
dc.contributor.institutionInst Pesquisas Jardim Rio Janeiro-
dc.description.affiliationUniv Estadual Paulista, Inst Quim, BR-14800 Araraquara, SP, Brazil-
dc.description.affiliationUniv São Paulo, Inst Quim, BR-05599 São Paulo, Brazil-
dc.description.affiliationInst Pesquisas Jardim Rio Janeiro, Rio de Janeiro, Brazil-
dc.description.affiliationUniv Estadual Paulista, Fac Ciencias Farmaceut, BR-14801 Araraquara, SP, Brazil-
dc.description.affiliationUnespUniv Estadual Paulista, Inst Quim, BR-14800 Araraquara, SP, Brazil-
dc.description.affiliationUnespUniv Estadual Paulista, Fac Ciencias Farmaceut, BR-14801 Araraquara, SP, Brazil-
dc.description.sponsorshipIdFAPESP: 03/11524-9-
dc.description.sponsorshipIdFAPESP: 05/57042-0-
dc.identifier.doi10.1016/j.phytochem.2007.08.012-
dc.identifier.wosWOS:000253267300018-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofPhytochemistry-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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