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http://acervodigital.unesp.br/handle/11449/26062Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Regasini, Luis Octavio | - |
| dc.contributor.author | Castro-Gamboa, Ian | - |
| dc.contributor.author | Siqueira Silva, Dulce Helena | - |
| dc.contributor.author | Furlan, Maysa | - |
| dc.contributor.author | Barreiro, Eliezer Jesus | - |
| dc.contributor.author | Pinheiro Ferreira, Paulo Michel | - |
| dc.contributor.author | Pessoa, Claudia | - |
| dc.contributor.author | Costa Lotufo, Leticia Veras | - |
| dc.contributor.author | Moraes, Manoel Odorico de | - |
| dc.contributor.author | Marx Young, Maria Claudia | - |
| dc.contributor.author | Bolzani, Vanderlan da Silva | - |
| dc.date.accessioned | 2014-05-20T14:20:11Z | - |
| dc.date.accessioned | 2016-10-25T17:41:29Z | - |
| dc.date.available | 2014-05-20T14:20:11Z | - |
| dc.date.available | 2016-10-25T17:41:29Z | - |
| dc.date.issued | 2009-03-01 | - |
| dc.identifier | http://dx.doi.org/10.1021/np800612x | - |
| dc.identifier.citation | Journal of Natural Products. Washington: Amer Chemical Soc, v. 72, n. 3, p. 473-476, 2009. | - |
| dc.identifier.issn | 0163-3864 | - |
| dc.identifier.uri | http://hdl.handle.net/11449/26062 | - |
| dc.identifier.uri | http://acervodigital.unesp.br/handle/11449/26062 | - |
| dc.description.abstract | As part of a bioprospecting program aimed at the discovery of potential anticancer drugs, two new guanidine-type alkaloids, nitensidines D and E (1, 2), and the known pterogynine (3), pterogynidine (4), and galegine (5), were isolated from the leaves of Pterogyne nitens. The structures of I and 2 were established on the basis of spectroscopic data interpretation. These compounds were tested against a small panel of human cancer cell lines. Compound 2 exhibited cytotoxicity for HL-60 (human myeloblastic leukemia) and SF-245 (human glioblastoma) cells. | en |
| dc.description.sponsorship | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | - |
| dc.description.sponsorship | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) | - |
| dc.format.extent | 473-476 | - |
| dc.language.iso | eng | - |
| dc.publisher | Amer Chemical Soc | - |
| dc.source | Web of Science | - |
| dc.title | Cytotoxic Guanidine Alkaloids from Pterogyne nitens | en |
| dc.type | outro | - |
| dc.contributor.institution | Universidade Estadual Paulista (UNESP) | - |
| dc.contributor.institution | Universidade Federal do Rio de Janeiro (UFRJ) | - |
| dc.contributor.institution | Universidade Federal do Ceará (UFC) | - |
| dc.contributor.institution | Inst Bot | - |
| dc.description.affiliation | São Paulo State Univ, Inst Chem, Nucley Bioassay Biosynth & Ecophys Nat Prod, UNESP, BR-14801970 Araraquara, SP, Brazil | - |
| dc.description.affiliation | Univ Fed Rio de Janeiro, LASSBio, Ctr Ciencias Saude, Fac Farm, BR-21944910 Rio de Janeiro, Brazil | - |
| dc.description.affiliation | Universidade Federal do Ceará (UFC), LOE, Dept Fisiol & Farmacol, BR-60430270 Fortaleza, Ceara, Brazil | - |
| dc.description.affiliation | Inst Bot, BR-01061970 São Paulo, Brazil | - |
| dc.description.affiliationUnesp | São Paulo State Univ, Inst Chem, Nucley Bioassay Biosynth & Ecophys Nat Prod, UNESP, BR-14801970 Araraquara, SP, Brazil | - |
| dc.description.sponsorshipId | FAPESP: 03/02176-7 | - |
| dc.identifier.doi | 10.1021/np800612x | - |
| dc.identifier.wos | WOS:000264627600025 | - |
| dc.rights.accessRights | Acesso restrito | - |
| dc.relation.ispartof | Journal of Natural Products | - |
| Appears in Collections: | Artigos, TCCs, Teses e Dissertações da Unesp | |
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