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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/26273
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dc.contributor.authorSilva, Geraldo H.-
dc.contributor.authorOliveira, Camila M. de-
dc.contributor.authorTeles, Helder L.-
dc.contributor.authorBolzani, Vanderlan da Silva-
dc.contributor.authorAraújo, Angela Regina-
dc.contributor.authorPfenning, Ludwig H.-
dc.contributor.authorYoung, Maria Claudia M.-
dc.contributor.authorCosta-Neto, Claudio M.-
dc.contributor.authorHaddad, Renato-
dc.contributor.authorEberlin, Marcos N.-
dc.date.accessioned2014-05-20T14:20:54Z-
dc.date.accessioned2016-10-25T17:41:46Z-
dc.date.available2014-05-20T14:20:54Z-
dc.date.available2016-10-25T17:41:46Z-
dc.date.issued2010-01-01-
dc.identifierhttp://dx.doi.org/10.1590/S0100-40422010001000006-
dc.identifier.citationQuímica Nova. Sociedade Brasileira de Química, v. 33, n. 10, p. 2038-2041, 2010.-
dc.identifier.issn0100-4042-
dc.identifier.urihttp://hdl.handle.net/11449/26273-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/26273-
dc.description.abstractA chemical study on the EtOAc extract produced by Xylaria sp., an endophytic fungus from Piper aduncum, resulted in the isolation of a new cytochalasin 1, along with five known 19,20-epoxycytochalasin D (2), C (3), N (4), Q (5), and R (6). The 1-6 were evaluated against the fungi C. cladosporioides and C. sphaerospermum and only 5 showed weak activity. The cytotoxicity in vitro against HeLA and CHO cells lines were investigated and the cytochalasins 2-4, and 6 showed a strong activity against HeLA. The DNAdamaging activity of 1-6 were also investigated against mutant strains of S. cerevisiae.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
dc.format.extent2038-2041-
dc.language.isopor-
dc.publisherSociedade Brasileira de Química-
dc.sourceSciELO-
dc.subjectXylaria sp.en
dc.subjectPiper aduncumen
dc.subjectendophytic fungusen
dc.titleCitocalasinas produzidas por Xylaria sp., um fungo endofítico de Piper aduncum (piperaceae)pt
dc.title.alternativeCytochalasins produced by Xylaria sp., an endophytic fungus from Piper aduncumen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionUniversidade Federal de Lavras (UFLA)-
dc.contributor.institutionInstituto de Botânica-
dc.contributor.institutionUniversidade de São Paulo (USP)-
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)-
dc.description.affiliationUniversidade Estadual Paulista Instituto de Química-
dc.description.affiliationUniversidade Federal de Lavras (UFLA) Departamento de Fitopatologia-
dc.description.affiliationInstituto de Botânica-
dc.description.affiliationUniversidade de São Paulo Faculdade de Medicina de Ribeirão Preto Departamento de Bioquímica e Imunologia-
dc.description.affiliationUniversidade Estadual de Campinas Instituto de Química-
dc.description.affiliationUnespUniversidade Estadual Paulista Instituto de Química-
dc.identifier.doi10.1590/S0100-40422010001000006-
dc.identifier.scieloS0100-40422010001000006-
dc.identifier.wosWOS:000286298500006-
dc.rights.accessRightsAcesso aberto-
dc.identifier.fileS0100-40422010001000006.pdf-
dc.relation.ispartofQuímica Nova-
dc.identifier.orcid0000-0001-7616-9652pt
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