You are in the accessibility menu

Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorOrgaes, Flavio Stillitano-
dc.contributor.authorViterbo, Fausto-
dc.contributor.authorMendes, Flavio Henrique-
dc.contributor.authorYabiku, Renato Florio-
dc.identifier.citationActa Cirúrgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 28, n. 4, p. 251-255, 2013.-
dc.description.abstractPURPOSE: To describe an animal model of rapid intravenous infusion with different volumes of crystalloid and discuss the clinical findings. METHODS: Fifty six male Wistar rats were used, divided randomly in seven groups (n = 8). The rats of groups 1 to 6 received lactated Ringer´s solution intravenously, in the rate of 25 ml/min, with different volumes proportional to blood volume (BV). The rats of group 0 were submitted to the same procedure, but did not receive the fluid (control group). The data included respiratory rate, heart rate, saturation of peripheral oxygen (SpO2) in two times (before and after the infusion), and upshots (respiratory arrest and death). Dunnett´s test and ANOVA were used. RESULTS: The clinical signs significantly changed in the 2, 2.5 and 3 fold BV groups. The respiratory arrest was observed in the 1.5, 2, 2.5 and 3 fold BV groups, but death was present only in 2.5 and 3 fold BV groups. CONCLUSIONS: The infusion of crystalloid in the same volume of blood volume did not cause significant variation in respiratory and heart rate, saturation of peripheral oxygen and did not induce respiratory arrest. The infusion of a volume of 3 fold blood volume was lethal to all animals.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.publisherSociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia-
dc.subjectFluid Therapyen
dc.subjectPulmonary Edemaen
dc.subjectModels, Animalen
dc.titleAnimal model of rapid crystalloid infusion in ratsen
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationUNESP Faculty of Medicine of Botucatu Department of Surgery and Orthopedics-
dc.description.affiliationUnespUNESP Faculty of Medicine of Botucatu Department of Surgery and Orthopedics-
dc.rights.accessRightsAcesso aberto-
dc.relation.ispartofActa Cirúrgica Brasileira-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.