Please use this identifier to cite or link to this item:
http://acervodigital.unesp.br/handle/11449/3013
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Roberto Monteiro, Gaby Ermelindo | - |
dc.contributor.author | Bechara, Gervasio Henrique | - |
dc.contributor.author | Franzin, Alessandra Maria | - |
dc.contributor.author | Ferreira de Miranda Santos, Isabel Kinney | - |
dc.date.accessioned | 2014-05-20T13:16:02Z | - |
dc.date.accessioned | 2016-10-25T16:37:28Z | - |
dc.date.available | 2014-05-20T13:16:02Z | - |
dc.date.available | 2016-10-25T16:37:28Z | - |
dc.date.issued | 2011-01-01 | - |
dc.identifier | http://dx.doi.org/10.1007/s10493-010-9380-x | - |
dc.identifier.citation | Experimental and Applied Acarology. Dordrecht: Springer, v. 53, n. 1, p. 63-69, 2011. | - |
dc.identifier.issn | 0168-8162 | - |
dc.identifier.uri | http://hdl.handle.net/11449/3013 | - |
dc.identifier.uri | http://acervodigital.unesp.br/handle/11449/3013 | - |
dc.description.abstract | Resistance to tick feeding has been previously shown to be an acquired, immunologically mediated phenomenon in goats, associated with cutaneous basophilia to nymphs of Amblyomma cajennense, the Cayenne tick, after repeated infestations. on the other hand, it is well known that antigen-presenting cells (APCs) play an important role in the host immune reaction to tick infestations. The most able APCs for Th cells are the well defined dendritic cells, mononuclear phagocytes and B-lymphocytes. Immunohistochemical analysis of draining lymph nodes of goats repeatedly infested with nymphs of the ixodid tick A. cajennense to search for APCs was done. Pre-scapular lymph nodes draining the tick attachment sites were collected 15 days after both the first and third infestations. Tick infestations resulted in increased number of CD21(+) B lymphocytes in lymph nodes after the tertiary infestation. However, the number of CD11b(+) and CD11c(+) cells were not altered after the successive infestations. Lower numbers of CD11c(+) cells had infiltrated lymph nodes responsible for draining the tick infested skin. These findings suggest that acquired immunity of goats against nymphs of A. cajennense is possibly established by B lymphocytes during the first infestation and that APCs may play a key role in this mechanism. | en |
dc.description.sponsorship | Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) | - |
dc.description.sponsorship | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) | - |
dc.description.sponsorship | European Commission | - |
dc.format.extent | 63-69 | - |
dc.language.iso | eng | - |
dc.publisher | Springer | - |
dc.source | Web of Science | - |
dc.subject | Amblyomma cajennense | en |
dc.subject | Nymphs | en |
dc.subject | Goats | en |
dc.subject | Immunohistochemistry | en |
dc.subject | Lymph nodes | en |
dc.subject | APCs | en |
dc.title | Antigen-presenting cells in draining lymph nodes of goats repeatedly infested by the Cayenne tick Amblyomma cajennense nymphs | en |
dc.type | outro | - |
dc.contributor.institution | Universidade Estadual Paulista (UNESP) | - |
dc.contributor.institution | Univ Eduardo Mondlane | - |
dc.contributor.institution | Universidade de São Paulo (USP) | - |
dc.contributor.institution | Brazilian Enterprise Agr Res | - |
dc.description.affiliation | São Paulo State Univ UNESP, Fac Agron & Vet Sci, Dept Anim Pathol, BR-14884900 Jaboticabal, SP, Brazil | - |
dc.description.affiliation | Univ Eduardo Mondlane, Fac Vet Med, Maputo, Mozambique | - |
dc.description.affiliation | Univ São Paulo, Fac Med Ribeirao Preto, Ribeirao Preto, SP, Brazil | - |
dc.description.affiliation | Brazilian Enterprise Agr Res, Natl Ctr Genet Resources & Biotechnol, Brasilia, DF, Brazil | - |
dc.description.affiliationUnesp | São Paulo State Univ UNESP, Fac Agron & Vet Sci, Dept Anim Pathol, BR-14884900 Jaboticabal, SP, Brazil | - |
dc.description.sponsorshipId | European Commission: 510561 | - |
dc.identifier.doi | 10.1007/s10493-010-9380-x | - |
dc.identifier.wos | WOS:000284651000007 | - |
dc.rights.accessRights | Acesso restrito | - |
dc.relation.ispartof | Experimental and Applied Acarology | - |
Appears in Collections: | Artigos, TCCs, Teses e Dissertações da Unesp |
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.