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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/31477
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dc.contributor.authorSaad, W. A.-
dc.contributor.authorLuiz, A. C.-
dc.contributor.authorCamargo, LAA-
dc.contributor.authorMenani, José Vanderlei-
dc.contributor.authorRenzi, Antonio-
dc.contributor.authorSilveira, JEN-
dc.date.accessioned2014-05-20T15:20:08Z-
dc.date.accessioned2016-10-25T17:53:11Z-
dc.date.available2014-05-20T15:20:08Z-
dc.date.available2016-10-25T17:53:11Z-
dc.date.issued1993-09-01-
dc.identifierhttp://www.scielo.br/scielo.php?script=sci_issues&pid=0100-879X&lng=en&nrm=iso-
dc.identifier.citationBrazilian Journal of Medical and Biological Research. São Paulo: Associação Bras Divulg Cientifica, v. 26, n. 9, p. 999-1007, 1993.-
dc.identifier.issn0100-879X-
dc.identifier.urihttp://hdl.handle.net/11449/31477-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/31477-
dc.description.abstract1. The effect of lisinopril, a potent inhibitor of angiotensin converting enzyme (ACE), injected into the medial preoptic area (MPOA) on water intake was investigated in male Holtzman rats (200-250 g).2. Injection of lisinopril (2 mug/mul) into the MPOA abolished the water intake induced by subcutaneous (sc) injection of isoprenaline (100%) and water deprivation (90%) and drastically reduced the water intake induced by sc injection of polyethyleneglycol (60%). A small reduction of water intake induced by lisinopril was also observed 90 and 120 min after sc hypertonic saline (N = 10 for each group).3. These results suggest that central ACE activation, particularly in the MPOA, plays an important role in the dipsogenic responses induced by the agents studied.en
dc.format.extent999-1007-
dc.language.isoeng-
dc.publisherAssociação Brasileira de Divulgação Científica (ABRADIC)-
dc.sourceWeb of Science-
dc.subjectWATER INTAKEpt
dc.subjectDEHYDRATIONpt
dc.subjectHYPOVOLEMIApt
dc.subjectANGIOTENSIN-IIpt
dc.subjectLISINOPRILpt
dc.subjectMEDIAL PREOPTIC AREApt
dc.titleCENTRAL ANGIOTENSIN-CONVERTING ENZYME-BLOCKADE AND THIRSTen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationUNESP,FAC ODONTOL,DEPT FISIOL,RUA HUMAITA 1680,BR-14801 ARARAQUARA,SP,BRAZIL-
dc.description.affiliationUnespUNESP,FAC ODONTOL,DEPT FISIOL,RUA HUMAITA 1680,BR-14801 ARARAQUARA,SP,BRAZIL-
dc.identifier.wosWOS:A1993LY94100012-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofBrazilian Journal of Medical and Biological Research-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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