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http://acervodigital.unesp.br/handle/11449/31477
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DC Field | Value | Language |
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dc.contributor.author | Saad, W. A. | - |
dc.contributor.author | Luiz, A. C. | - |
dc.contributor.author | Camargo, LAA | - |
dc.contributor.author | Menani, José Vanderlei | - |
dc.contributor.author | Renzi, Antonio | - |
dc.contributor.author | Silveira, JEN | - |
dc.date.accessioned | 2014-05-20T15:20:08Z | - |
dc.date.accessioned | 2016-10-25T17:53:11Z | - |
dc.date.available | 2014-05-20T15:20:08Z | - |
dc.date.available | 2016-10-25T17:53:11Z | - |
dc.date.issued | 1993-09-01 | - |
dc.identifier | http://www.scielo.br/scielo.php?script=sci_issues&pid=0100-879X&lng=en&nrm=iso | - |
dc.identifier.citation | Brazilian Journal of Medical and Biological Research. São Paulo: Associação Bras Divulg Cientifica, v. 26, n. 9, p. 999-1007, 1993. | - |
dc.identifier.issn | 0100-879X | - |
dc.identifier.uri | http://hdl.handle.net/11449/31477 | - |
dc.identifier.uri | http://acervodigital.unesp.br/handle/11449/31477 | - |
dc.description.abstract | 1. The effect of lisinopril, a potent inhibitor of angiotensin converting enzyme (ACE), injected into the medial preoptic area (MPOA) on water intake was investigated in male Holtzman rats (200-250 g).2. Injection of lisinopril (2 mug/mul) into the MPOA abolished the water intake induced by subcutaneous (sc) injection of isoprenaline (100%) and water deprivation (90%) and drastically reduced the water intake induced by sc injection of polyethyleneglycol (60%). A small reduction of water intake induced by lisinopril was also observed 90 and 120 min after sc hypertonic saline (N = 10 for each group).3. These results suggest that central ACE activation, particularly in the MPOA, plays an important role in the dipsogenic responses induced by the agents studied. | en |
dc.format.extent | 999-1007 | - |
dc.language.iso | eng | - |
dc.publisher | Associação Brasileira de Divulgação Científica (ABRADIC) | - |
dc.source | Web of Science | - |
dc.subject | WATER INTAKE | pt |
dc.subject | DEHYDRATION | pt |
dc.subject | HYPOVOLEMIA | pt |
dc.subject | ANGIOTENSIN-II | pt |
dc.subject | LISINOPRIL | pt |
dc.subject | MEDIAL PREOPTIC AREA | pt |
dc.title | CENTRAL ANGIOTENSIN-CONVERTING ENZYME-BLOCKADE AND THIRST | en |
dc.type | outro | - |
dc.contributor.institution | Universidade Estadual Paulista (UNESP) | - |
dc.description.affiliation | UNESP,FAC ODONTOL,DEPT FISIOL,RUA HUMAITA 1680,BR-14801 ARARAQUARA,SP,BRAZIL | - |
dc.description.affiliationUnesp | UNESP,FAC ODONTOL,DEPT FISIOL,RUA HUMAITA 1680,BR-14801 ARARAQUARA,SP,BRAZIL | - |
dc.identifier.wos | WOS:A1993LY94100012 | - |
dc.rights.accessRights | Acesso restrito | - |
dc.relation.ispartof | Brazilian Journal of Medical and Biological Research | - |
Appears in Collections: | Artigos, TCCs, Teses e Dissertações da Unesp |
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