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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/32749
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dc.contributor.authorde Carvalho, PRF-
dc.contributor.authorFurlan, Maysa-
dc.contributor.authorYoung, MCM-
dc.contributor.authorKingston, DGI-
dc.contributor.authorBolzani, Vanderlan da Silva-
dc.date.accessioned2014-05-20T15:21:37Z-
dc.date.accessioned2016-10-25T17:55:07Z-
dc.date.available2014-05-20T15:21:37Z-
dc.date.available2016-10-25T17:55:07Z-
dc.date.issued1998-11-01-
dc.identifierhttp://dx.doi.org/10.1016/S0031-9422(98)00249-0-
dc.identifier.citationPhytochemistry. Oxford: Pergamon-Elsevier B.V., v. 49, n. 6, p. 1659-1662, 1998.-
dc.identifier.issn0031-9422-
dc.identifier.urihttp://hdl.handle.net/11449/32749-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/32749-
dc.description.abstractIn addition to the known diterpene casearin G (1), two new clerodane diterpene casearins type, casearin S (2) and casearin T (3), were isolated from an acetylated bioactive CH2Cl2/MeOH extract from leaves of Casealia sylvestris. The diterpenes 1-3 exhibited moderate but selective activity towards the DNA-repair deficient yeast Saccharomyces cerevisiae mutants RAD 52YK and RS 321. The structures of 1-3 were established on the basis of NMR spectroscopic experiments (C) 1998 Elsevier B.V. Ltd. All rights reserved.en
dc.format.extent1659-1662-
dc.language.isoeng-
dc.publisherElsevier B.V.-
dc.sourceWeb of Science-
dc.subjectCasearia sylvestrispt
dc.subjectflacourtiaceaept
dc.subjectditerpenept
dc.subjectclerodanept
dc.subjectcasearinspt
dc.subjectDNA-damaging activitypt
dc.titleAcetylated DNA-damaging clerodane diterpenes from Casearia sylvestrisen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionInst Bot-
dc.contributor.institutionVirginia Polytech Inst & State Univ-
dc.description.affiliationUniv Estadual Paulista, Inst Quim, BR-14800900 Araraquara, SP, Brazil-
dc.description.affiliationInst Bot, Secao Fisiol & Bioquim Plantas, BR-01051 São Paulo, Brazil-
dc.description.affiliationVirginia Polytech Inst & State Univ, Dept Chem, Blacksburg, VA 24061 USA-
dc.description.affiliationUnespUniv Estadual Paulista, Inst Quim, BR-14800900 Araraquara, SP, Brazil-
dc.identifier.doi10.1016/S0031-9422(98)00249-0-
dc.identifier.wosWOS:000077480300027-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofPhytochemistry-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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