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http://acervodigital.unesp.br/handle/11449/336Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Toyama, M. H. | - |
| dc.contributor.author | Toyama, D. O. | - |
| dc.contributor.author | Torres, V. M. | - |
| dc.contributor.author | Pontes, G. C. | - |
| dc.contributor.author | Farias, W. R. L. | - |
| dc.contributor.author | Melo, F. R. | - |
| dc.contributor.author | Oliveira, S. C. B. | - |
| dc.contributor.author | Fagundes, F. H. R. | - |
| dc.contributor.author | Diz Filho, E. B. S. | - |
| dc.contributor.author | Cavada, B. S. | - |
| dc.date.accessioned | 2014-05-20T13:12:21Z | - |
| dc.date.accessioned | 2016-10-25T16:32:49Z | - |
| dc.date.available | 2014-05-20T13:12:21Z | - |
| dc.date.available | 2016-10-25T16:32:49Z | - |
| dc.date.issued | 2010-11-01 | - |
| dc.identifier | http://dx.doi.org/10.1007/s10930-010-9294-9 | - |
| dc.identifier.citation | Protein Journal. New York: Springer, v. 29, n. 8, p. 567-571, 2010. | - |
| dc.identifier.issn | 1572-3887 | - |
| dc.identifier.uri | http://hdl.handle.net/11449/336 | - |
| dc.identifier.uri | http://acervodigital.unesp.br/handle/11449/336 | - |
| dc.description.abstract | Low molecular weight fragments of sulfated galactans (Boc-5 and Boc-10) from the red algae Botryocladia occidentalis significantly inhibited Crotalus durissus cascavella sPLA2 enzymatic activity. Equimolar ratios of sPLA2 to Boc-5 or Boc-10 resulted in allosteric inhibition of sPLA2. Under the conditions tested, we observed that both Boc-5 and Boc-10 strongly decreased edema, myonecrosis, and neurotoxicity induced by native sPLA2. | en |
| dc.description.sponsorship | FAPEPS | - |
| dc.description.sponsorship | Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) | - |
| dc.format.extent | 567-571 | - |
| dc.language.iso | eng | - |
| dc.publisher | Springer | - |
| dc.source | Web of Science | - |
| dc.subject | Botryocladia occidentalis | en |
| dc.subject | Crotalus durissus cascavella | en |
| dc.subject | Secretory phospholipase A2 (sPLA2) | en |
| dc.subject | Edema | en |
| dc.subject | Myonecrosis | en |
| dc.title | Effects of Low Molecular Weight Sulfated Galactan Fragments From Botryocladia Occidentalis on the Pharmacological and Enzymatic Activity of Spla2 From Crotalus Durissus Cascavella | en |
| dc.type | outro | - |
| dc.contributor.institution | Universidade Estadual Paulista (UNESP) | - |
| dc.contributor.institution | Univ Presbiteriana Mackenzie | - |
| dc.contributor.institution | Universidade Federal do Ceará (UFC) | - |
| dc.contributor.institution | Universidade Federal do Rio de Janeiro (UFRJ) | - |
| dc.contributor.institution | Universidade Estadual de Campinas (UNICAMP) | - |
| dc.contributor.institution | UFC | - |
| dc.description.affiliation | UNESP, Sao Vicente, Brazil | - |
| dc.description.affiliation | Univ Presbiteriana Mackenzie, São Paulo, Brazil | - |
| dc.description.affiliation | Universidade Federal do Ceará (UFC), Dept Engn Pesca & BioMol BioMar, Fortaleza, Ceara, Brazil | - |
| dc.description.affiliation | Hosp Univ Clementino Fraga Filho HUCFF UFRJ, Rio de Janeiro, Brazil | - |
| dc.description.affiliation | Univ Estadual Campinas, Dept Bioquim, Inst Biol, São Paulo, Brazil | - |
| dc.description.affiliation | UFC, Dept Bioquim, São Paulo, Brazil | - |
| dc.description.affiliationUnesp | UNESP, Sao Vicente, Brazil | - |
| dc.description.sponsorshipId | FAPEPS: 54714-3 | - |
| dc.description.sponsorshipId | CNPq: 558193/2009-9 | - |
| dc.identifier.doi | 10.1007/s10930-010-9294-9 | - |
| dc.identifier.wos | WOS:000284644400005 | - |
| dc.rights.accessRights | Acesso restrito | - |
| dc.relation.ispartof | Protein Journal | - |
| Appears in Collections: | Artigos, TCCs, Teses e Dissertações da Unesp | |
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