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http://acervodigital.unesp.br/handle/11449/36180
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DC Field | Value | Language |
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dc.contributor.author | Giardini, M. A. | - |
dc.contributor.author | Lira, CBB | - |
dc.contributor.author | Conte, F. F. | - |
dc.contributor.author | Camillo, L. R. | - |
dc.contributor.author | Neto, JLD | - |
dc.contributor.author | Ramos, CHI | - |
dc.contributor.author | Cano, MIN | - |
dc.date.accessioned | 2014-05-20T15:25:51Z | - |
dc.date.accessioned | 2016-10-25T18:00:25Z | - |
dc.date.available | 2014-05-20T15:25:51Z | - |
dc.date.available | 2016-10-25T18:00:25Z | - |
dc.date.issued | 2006-04-01 | - |
dc.identifier | http://dx.doi.org/10.1007/s00436-005-0036-4 | - |
dc.identifier.citation | Parasitology Research. New York: Springer, v. 98, n. 5, p. 447-454, 2006. | - |
dc.identifier.issn | 0932-0113 | - |
dc.identifier.uri | http://hdl.handle.net/11449/36180 | - |
dc.identifier.uri | http://acervodigital.unesp.br/handle/11449/36180 | - |
dc.description.abstract | The Leishmania amazonensis telomerase gene was cloned by a polymerase chain reaction-based strategy using primers designed from a Leishmania major sequence that shared similarities with conserved telomerase motifs. The genes from three other species were cloned for comparative purposes. A ClustalW multiple-sequence alignment demonstrated that the Leishmania telomerases show greater homology with each other than with the proteins of other kinetoplastids and eukaryotes. Characterization experiments indicated that the putative Leishmania telomerase gene was probably in single copy and located in the largest chromosomes. A single messenger ribonucleic acid transcript was found in promastigotes. Phylogenetic analysis suggested that Leishmania telomerase might represent a liaison between the oldest and the newest branches of telomerases. | en |
dc.format.extent | 447-454 | - |
dc.language.iso | eng | - |
dc.publisher | Springer | - |
dc.source | Web of Science | - |
dc.title | The putative telomerase reverse transcriptase component of Leishmania amazonensis: gene cloning and characterization | en |
dc.type | outro | - |
dc.contributor.institution | Universidade Estadual de Campinas (UNICAMP) | - |
dc.contributor.institution | LNLS | - |
dc.contributor.institution | Universidade Estadual Paulista (UNESP) | - |
dc.description.affiliation | Univ Estadual Campinas, Fac Ciências Med, Dept Patol Clin Nucl Med & Cirurgia Expt, BR-13083970 Campinas, SP, Brazil | - |
dc.description.affiliation | LNLS, Ctr Biol Mol Estrutural, Campinas, SP, Brazil | - |
dc.identifier.doi | 10.1007/s00436-005-0036-4 | - |
dc.identifier.wos | WOS:000236207300009 | - |
dc.rights.accessRights | Acesso restrito | - |
dc.relation.ispartof | Parasitology Research | - |
Appears in Collections: | Artigos, TCCs, Teses e Dissertações da Unesp |
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