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dc.contributor.authorAmarante, MRV-
dc.contributor.authorYang, Y. P.-
dc.contributor.authorKata, SR-
dc.contributor.authorLopes, C. R.-
dc.contributor.authorWomack, J. E.-
dc.identifier.citationMammalian Genome. New York: Springer, v. 11, n. 5, p. 364-368, 2000.-
dc.description.abstractComparative mapping data on evolutionary conserved coding sequences and synteny maps between human and cattle are insufficient to define the extent and distribution of conserved segments between these two species, because the order of loci is often rearranged. A 5000-rad cattle whole-genome radiation hybrid (WG-RH) panel was constructed to provide high-resolution comparative maps and also to integrate linkage maps of microsatellites with evolutionary conserved genes and transcripts in a single ordered map. We used the WG-RH panel to construct radiation hybrid maps of bovine Chromosomes (Chrs) 15 and 29 (BTA15 and BTA29), integrating microsatellites from published linkage maps with selected genes. The comprehensive map of BTA15 consists of 24 markers. 13 of which were placed in the framework map. Eleven molecular markers compose the comprehensive map of BTA29. seven of which were placed in the framework map. We identified the homologous regions between bovine Chr 15 (BTA15) and human Chrs 5 and 11 (HSA5 and HSA11), as well as between BTA29 and HSA11, the present study demonstrates that WG-RH mapping is an efficient method for integrating multiple genetic maps into one map and for incorporating monomorphic Type I loci into ordered maps for comparison between species.en
dc.sourceWeb of Science-
dc.titleRH maps of bovine chromosomes 15 and 29: conservation of human chromosomes 11 and 5en
dc.contributor.institutionTexas A&M Univ-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationTexas A&M Univ, Texas Vet Med Ctr, Dept Vet Pathobiol, College Stn, TX 77843 USA-
dc.description.affiliationUniv Estadual Paulista, Inst Biociencias, Dept Genet, BR-18600000 São Paulo, Brazil-
dc.description.affiliationUnespUniv Estadual Paulista, Inst Biociencias, Dept Genet, BR-18600000 São Paulo, Brazil-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofMammalian Genome-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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