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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/37081
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dc.contributor.authorSchellini, Silvana Artioli-
dc.contributor.authorGregorio, E. A.-
dc.contributor.authorSpadella, C. T.-
dc.contributor.authorMachado, JLM-
dc.contributor.authorDemoraessilva, M. A.-
dc.date.accessioned2014-05-20T15:27:01Z-
dc.date.accessioned2016-10-25T18:01:44Z-
dc.date.available2014-05-20T15:27:01Z-
dc.date.available2016-10-25T18:01:44Z-
dc.date.issued1995-09-01-
dc.identifierhttp://www.scielo.br/scielo.php?script=sci_issues&pid=0100-879X&lng=en&nrm=iso-
dc.identifier.citationBrazilian Journal of Medical and Biological Research. São Paulo: Associação Bras Divulg Cientifica, v. 28, n. 9, p. 977-980, 1995.-
dc.identifier.issn0100-879X-
dc.identifier.urihttp://hdl.handle.net/11449/37081-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/37081-
dc.description.abstractMuller cells provide nutrition for neural cells. We studied the structure and ultrastructure of Muller cells in the retina of thirty 3-month old Wistar rats; divided equally into 3 groups: normal rats, alloxan diabetic rats and treated alloxan diabetic rats. 1 and 12 months after induction of diabetes. We observed that the Muller cell nuclei under light microscope examination had hexagonal shape and higher density than the other nuclei. Differences between groups could be observed only by electron microscopy. In the diabetic rats, Muller cells presented dispersion of nuclear chromatin and electrondense nuclear granulations, with the presence of increased glycogen, dense bodies and lysosomes in the cytoplasm. The alterations were more frequent in the perivascular region and at 12 months. The treated diabetic rats exhibited some alterations we observed in diabetic rats. but these alterations were less intense. We conclude that, despite the treatment, the diabetic retinopathy continues to evolve.en
dc.format.extent977-980-
dc.language.isoeng-
dc.publisherAssociação Brasileira de Divulgação Científica (ABRADIC)-
dc.sourceWeb of Science-
dc.subjectMULLER CELLpt
dc.subjectDIABETIC RETINOPATHYpt
dc.subjectALLOXAN DIABETESpt
dc.subjectDIABETES IN RATSpt
dc.titleMULLER CELLS AND DIABETIC-RETINOPATHYen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationUNIV ESTADUAL PAULISTA,FAC MED BOTUCATU,DEPT MORFOL,BR-18618000 BOTUCATU,SP,BRAZIL-
dc.description.affiliationUNIV ESTADUAL PAULISTA,FAC MED BOTUCATU,DEPT CIRURGIA & ORTEPED,BR-18618000 BOTUCATU,SP,BRAZIL-
dc.description.affiliationUnespUNIV ESTADUAL PAULISTA,FAC MED BOTUCATU,DEPT MORFOL,BR-18618000 BOTUCATU,SP,BRAZIL-
dc.description.affiliationUnespUNIV ESTADUAL PAULISTA,FAC MED BOTUCATU,DEPT CIRURGIA & ORTEPED,BR-18618000 BOTUCATU,SP,BRAZIL-
dc.identifier.wosWOS:A1995RZ77100007-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofBrazilian Journal of Medical and Biological Research-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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