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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/38238
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dc.contributor.authorTorres, F. R.-
dc.contributor.authorOndei, L. S.-
dc.contributor.authorZamaro, P. J. A.-
dc.contributor.authorSilva, R. U.-
dc.contributor.authorCavasini, C. E.-
dc.contributor.authorRossit, A. R. B.-
dc.contributor.authorMachado, R. L. D.-
dc.contributor.authorBonini-Domingos, C. R.-
dc.date.accessioned2015-09-10T12:33:20Z-
dc.date.accessioned2016-10-25T20:57:36Z-
dc.date.available2015-09-10T12:33:20Z-
dc.date.available2016-10-25T20:57:36Z-
dc.date.issued2006-01-01-
dc.identifierhttp://www.geneticsmr.com/articles/307-
dc.identifier.citationGenetics and Molecular Research, v. 5, n. 4, p. 713-716, 2006.-
dc.identifier.issn1676-5680-
dc.identifier.urihttp://hdl.handle.net/11449/38238-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/38238-
dc.description.abstractWe describe a heterozygous case of Hb I-Philadelphia [alpha 16 (A14) LYS-->GLU] in a blood donor from the Acre State Blood Bank, in the Brazilian Amazon region. We confirmed the mutation by electrophoretic and chromatographic methods and by DNA sequencing. A literature search showed that this is the first description of this alpha globin mutant in a Brazilian Caucasian group. We also emphasize the importance of the hemoglobin study in blood donors for the purpose of the genetic counseling and quality assurance of the blood to be transfused. Screening tests for hemoglobin mutants are also important for gathering anthropological information about the Brazilian population.en
dc.format.extent713-716-
dc.language.isoeng-
dc.publisherFunpec-editora-
dc.sourceWeb of Science-
dc.sourceScopus-
dc.subjectHb I-Philadelphiapt
dc.subjectrare hemoglobinpt
dc.subjectHPLCpt
dc.subjectblood donorspt
dc.titleHemoglobin I-Philadelphia [alpha 16 (A14) LYS→GLU] heterozygote among blood donors from Brazilen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionBanco de Sangue do Estado do Acre-
dc.contributor.institutionFaculdade de Medicina-
dc.description.affiliationDepartamento de Biologia Laboratório de Hemoglobinas e Genética Das Doenças Hematológicas UNESP, S. José do Rio Preto, SP-
dc.description.affiliationBanco de Sangue do Estado do Acre, Rio Branco, AC-
dc.description.affiliationDepartamento de Doenças Infecciosas, Dermatológicas e Parasitárias Centro de Investigação de Microrganismos Faculdade de Medicina, S. José do Rio Preto, SP-
dc.description.affiliationUnespDepartamento de Biologia Laboratório de Hemoglobinas e Genética Das Doenças Hematológicas UNESP, S. José do Rio Preto, SP-
dc.identifier.wosWOS:000203012000013-
dc.rights.accessRightsAcesso aberto-
dc.identifier.fileWOS000203012000013.pdf-
dc.relation.ispartofGenetics and Molecular Research-
dc.identifier.scopus2-s2.0-33845424973-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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