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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/39439
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dc.contributor.authorDal-Pizzol, Felipe-
dc.contributor.authorQuevedo, Joao-
dc.contributor.authorStreck, Emilio-
dc.contributor.authorWalz, Roger-
dc.contributor.authorMoreira, Jose Claudio F.-
dc.date.accessioned2014-05-20T15:29:59Z-
dc.date.accessioned2016-10-25T18:05:20Z-
dc.date.available2014-05-20T15:29:59Z-
dc.date.available2016-10-25T18:05:20Z-
dc.date.issued2007-03-01-
dc.identifierhttp://dx.doi.org/10.1007/s11011-006-9033-2-
dc.identifier.citationMetabolic Brain Disease. New York: Springer/plenum Publishers, v. 22, n. 1, p. 25-29, 2007.-
dc.identifier.issn0885-7490-
dc.identifier.urihttp://hdl.handle.net/11449/39439-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/39439-
dc.description.abstractOxidative damage to biological membranes has been reported as a cause of alterations in many different diseases. We had previously reported lipid peroxidation in the kainic acid model of temporal epilepsy. In this study we evaluated earlier and later modifications in the lipid composition after status epileticus induced by kainic acid. Lipid composition was determined by thin-layer chromatography, in the cortex and hippocampus 12-14 h, 7-8, 75-80, or 140-150 days after the end of status epileticus. In the hippocampus there was a significant change in the lipid protein ratio after status epileticus and this was accompanied by an alteration in lipid composition in all tested times. These results suggested that lipid peroxidation induced by kainic acid could be accompanied by chronic changes in the lipid composition that could be related to the development of seizures.en
dc.format.extent25-29-
dc.language.isoeng-
dc.publisherSpringer-
dc.sourceWeb of Science-
dc.subjectoxidative stresspt
dc.subjectkainic acidpt
dc.subjectseizurespt
dc.subjectlipid peroxidationpt
dc.subjectlipid compositionpt
dc.subjectmembrane fluiditypt
dc.titleChanges in lipid composition in hippocampus early and late after status epilepticus induced by kainic acid in wistar ratsen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionUniversidade Federal de Santa Catarina (UFSC)-
dc.contributor.institutionUniversidade Federal do Rio Grande do Sul (UFRGS)-
dc.description.affiliationUNESP, Programa Posgrad Ciências Saude, Lab Fisiopatol Expt, BR-88006000 Circiuma, SC, Brazil-
dc.description.affiliationUniv Fed Santa Catarina, Dept Clin Med, BR-88040900 Florianopolis, SC, Brazil-
dc.description.affiliationUniv Fed Rio Grande do Sul, Ctr Estudos Estresse Oxidat, Dept Bioquim, BR-90046900 Porto Alegre, RS, Brazil-
dc.description.affiliationUnespUNESP, Programa Posgrad Ciências Saude, Lab Fisiopatol Expt, BR-88006000 Circiuma, SC, Brazil-
dc.identifier.doi10.1007/s11011-006-9033-2-
dc.identifier.wosWOS:000246370800003-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofMetabolic Brain Disease-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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