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http://acervodigital.unesp.br/handle/11449/39908
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DC Field | Value | Language |
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dc.contributor.author | Damazo, A. S. | - |
dc.contributor.author | Flower, R. J. | - |
dc.contributor.author | Solito, E. | - |
dc.contributor.author | Oliani, S. M. | - |
dc.date.accessioned | 2014-05-20T15:30:34Z | - |
dc.date.accessioned | 2016-10-25T18:06:07Z | - |
dc.date.available | 2014-05-20T15:30:34Z | - |
dc.date.available | 2016-10-25T18:06:07Z | - |
dc.date.issued | 2008-03-01 | - |
dc.identifier | http://dx.doi.org/10.1007/s00011-007-7114-2 | - |
dc.identifier.citation | Inflammation Research. Basel: Birkhauser Verlag Ag, v. 57, n. 3, p. 97-103, 2008. | - |
dc.identifier.issn | 1023-3830 | - |
dc.identifier.uri | http://hdl.handle.net/11449/39908 | - |
dc.identifier.uri | http://acervodigital.unesp.br/handle/11449/39908 | - |
dc.description.abstract | Objective and design: We have previously reported a role for annexin-A1 in liver proliferation and tumorogenicity as well as its action as an acute phase protein in a model of endotoxemia in interleukin-6 null mice.Material and methods: In this study, we have investigated the analysis of the gene and protein expression in annexin-A1 null mice and the wild type livers during foetal and adult life, and in the presence of a proinflammatory stimulus.Results: The data indicate a link between the expression of the annexin-A1 as serine-phosphorylated-protein during early events of the inflammatory response and as tyrosine-phosphorylated-form at later time-points, during the resolution of inflammation.Conclusions: The study of annexin-A1 post-translation modification may promote a new annexin-A1 peptide discovery programme to treat specific pathologies. | en |
dc.format.extent | 97-103 | - |
dc.language.iso | eng | - |
dc.publisher | Birkhauser Verlag Ag | - |
dc.source | Web of Science | - |
dc.subject | hepatocytes | en |
dc.subject | Neutrophil | en |
dc.subject | Liver | en |
dc.subject | Inflammation | en |
dc.subject | Gene expression | en |
dc.title | Annexin-A1 gene expression during liver development and post-translation modification after experimental endotoxemia | en |
dc.type | outro | - |
dc.contributor.institution | Universidade de São Paulo (USP) | - |
dc.contributor.institution | Univ London St Bartholomews Hosp Med Coll | - |
dc.contributor.institution | Univ London Imperial Coll Sci Technol & Med | - |
dc.contributor.institution | Universidade Federal de São Paulo (UNIFESP) | - |
dc.contributor.institution | Universidade Estadual Paulista (UNESP) | - |
dc.description.affiliation | Univ São Paulo, IBILCE, Dept Biol, BR-05508 São Paulo, Brazil | - |
dc.description.affiliation | Univ London St Bartholomews Hosp Med Coll, Coll Med, William Harvey Res Inst, Ctr Biochem Pharmacol, London EC1M 6BQ, England | - |
dc.description.affiliation | Univ London Imperial Coll Sci Technol & Med, Div Neurosci & Mental Hlth, Dept Cellular & Mol Neurosci, London W12 ONN, England | - |
dc.description.affiliation | Univ Fed São Paulo, BR-04023900 São Paulo, Brazil | - |
dc.description.affiliationUnesp | Univ São Paulo, IBILCE, Dept Biol, BR-05508 São Paulo, Brazil | - |
dc.identifier.doi | 10.1007/s00011-007-7114-2 | - |
dc.identifier.wos | WOS:000254436500002 | - |
dc.rights.accessRights | Acesso restrito | - |
dc.relation.ispartof | Inflammation Research | - |
Appears in Collections: | Artigos, TCCs, Teses e Dissertações da Unesp |
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