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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/3994
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dc.contributor.authorMarcondes, Jackson-
dc.contributor.authorHansen, Ekkehard-
dc.date.accessioned2014-05-20T13:17:34Z-
dc.date.available2014-05-20T13:17:34Z-
dc.date.issued2008-12-01-
dc.identifierhttp://dx.doi.org/10.1590/S1413-86702008000600004-
dc.identifier.citationBrazilian Journal of Infectious Diseases. Brazilian Society of Infectious Diseases, v. 12, n. 6, p. 469-471, 2008.-
dc.identifier.issn1413-8670-
dc.identifier.urihttp://hdl.handle.net/11449/3994-
dc.description.abstractThe obtainment of transgenic edible plants carrying recombinant antigens is a desired issue in search for economic alternatives viewing vaccine production. Here we report a strategy for genetic transformation of lettuce plants (Lactuca sativa L.) using the surface antigen HBsAg of hepatitis B virus. Transgenic lettuce seedlings were obtained through the application of a regulated balance of plant growth regulators. Genetic transformation process was acquired by cocultivation of cotyledons with Agrobacterium tumefaciens harboring the recombinant plasmid. It is the first description of a lettuce Brazilian variety Vitória de Verão genetically modified.en
dc.format.extent469-471-
dc.language.isoeng-
dc.publisherBrazilian Society of Infectious Diseases-
dc.sourceSciELO-
dc.subjectEdible vaccineen
dc.subjectHepatitis Ben
dc.subjectOral immunizationen
dc.subjectRecombinant antigenen
dc.subjectTransgenic plantsen
dc.titleTransgenic lettuce seedlings carrying hepatitis B virus antigen HBsAgen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionUniversidade Estadual do Norte Fluminense-
dc.description.affiliationUNESP School of Agricultural Sciences and Veterinary Biochemical Laboratory of Plants and Microorganisms-
dc.description.affiliationState University of North Fluminense Laboratory of Biotechnology-
dc.description.affiliationUnespUNESP School of Agricultural Sciences and Veterinary Biochemical Laboratory of Plants and Microorganisms-
dc.identifier.doi10.1590/S1413-86702008000600004-
dc.identifier.scieloS1413-86702008000600004-
dc.identifier.wosWOS:000264200300004-
dc.rights.accessRightsAcesso aberto-
dc.identifier.fileS1413-86702008000600004.pdf-
dc.relation.ispartofBrazilian Journal of Infectious Diseases-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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