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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/41111
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dc.contributor.authorAmorim, Renée Laufer-
dc.contributor.authorPinczowski, P.-
dc.contributor.authorNeto, R. T.-
dc.contributor.authorRahal, Sheila Canevese-
dc.date.accessioned2014-05-20T15:32:07Z-
dc.date.accessioned2016-10-25T18:08:15Z-
dc.date.available2014-05-20T15:32:07Z-
dc.date.available2016-10-25T18:08:15Z-
dc.date.issued2010-03-01-
dc.identifierhttp://dx.doi.org/10.1111/j.1476-5829.2009.00202.x-
dc.identifier.citationVeterinary and Comparative Oncology. Malden: Wiley-blackwell Publishing, Inc, v. 8, n. 1, p. 23-27, 2010.-
dc.identifier.issn1476-5810-
dc.identifier.urihttp://hdl.handle.net/11449/41111-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/41111-
dc.description.abstractVascular endothelial growth factor (VEGF) and prostaglandin E2 (PGE-2) appear to play a critical role in tumour neovascularization. In this study, we have investigated the expression of VEGF and PGE-2 in 53 canine cutaneous mast cell tumours (MCTs). Immunohistochemistry of tissue sections revealed that VEGF and PGE-2 were expressed in all mast cell tumours studied. When the expression patterns of VEGF and PGE-2 were compared with tumour grade according to Patnaik criteria, the only significant correlation observed was between PGE-2 staining intensity and tumour pathological grade, with grade II and III tumours having higher PGE-2 staining, both in intensity and percentage of cells stained, than grade I tumours (P < 0.05).en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.format.extent23-27-
dc.language.isoeng-
dc.publisherWiley-Blackwell Publishing, Inc-
dc.sourceWeb of Science-
dc.subjectangiogenesisen
dc.subjectcanineen
dc.subjectmast cell tumouren
dc.subjectPGE-2en
dc.subjectVEGFen
dc.titleImmunohistochemical evaluation of prostaglandin E2 and vascular endothelial growth factor in canine cutaneous mast cell tumoursen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationUniv Estadual Paulista, Sch Vet Med & Anim Sci, Dept Clin Vet Med, BR-18618000 São Paulo, Brazil-
dc.description.affiliationUniv Estadual Paulista, Sch Vet Med & Anim Sci, Dept Vet Surg & Anesthesiol, BR-18618000 São Paulo, Brazil-
dc.description.affiliationUnespUniv Estadual Paulista, Sch Vet Med & Anim Sci, Dept Clin Vet Med, BR-18618000 São Paulo, Brazil-
dc.description.affiliationUnespUniv Estadual Paulista, Sch Vet Med & Anim Sci, Dept Vet Surg & Anesthesiol, BR-18618000 São Paulo, Brazil-
dc.identifier.doi10.1111/j.1476-5829.2009.00202.x-
dc.identifier.wosWOS:000273912000003-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofVeterinary and Comparative Oncology-
dc.identifier.orcid0000-0002-9211-4093pt
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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