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http://acervodigital.unesp.br/handle/11449/41435
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DC Field | Value | Language |
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dc.contributor.author | Vides, Juliana Peloi | - |
dc.contributor.author | Schwardt, Tatianna Frate | - |
dc.contributor.author | Vicente Sobrinho, Ludmila Silva | - |
dc.contributor.author | Marinho, Márcia | - |
dc.contributor.author | Laurenti, Marcia Dalastra | - |
dc.contributor.author | Biondo, Alexander Welker | - |
dc.contributor.author | Leutenegger, Christian | - |
dc.contributor.author | Marcondes, Mary | - |
dc.date.accessioned | 2014-05-20T15:32:34Z | - |
dc.date.accessioned | 2016-10-25T18:08:51Z | - |
dc.date.available | 2014-05-20T15:32:34Z | - |
dc.date.available | 2016-10-25T18:08:51Z | - |
dc.date.issued | 2011-05-31 | - |
dc.identifier | http://dx.doi.org/10.1016/j.vetpar.2010.12.042 | - |
dc.identifier.citation | Veterinary Parasitology. Amsterdam: Elsevier B.V., v. 178, n. 1-2, p. 22-28, 2011. | - |
dc.identifier.issn | 0304-4017 | - |
dc.identifier.uri | http://hdl.handle.net/11449/41435 | - |
dc.identifier.uri | http://acervodigital.unesp.br/handle/11449/41435 | - |
dc.description.abstract | Although dogs are considered the main domestic reservoirs for Visceral Leishmaniosis (VL), which is caused in the Americas by Leishmania chagasi, infected cats have also been recently found in endemic areas of several countries and became a public health concern. Accordingly, the purpose of this study was to evaluate cats with dermatologic lesions from an endemic area of VL and the natural infection of L. chagasi. A total of 55 cats were selected between April 2008 and November 2009 from two major animal shelters of Aracatuba, Southeastern Brazil. All cats underwent general and dermatologic examinations, followed by direct parasitological examination of lymphoid organs, immunosorbent assay (ELISA) and indirect immunofluorescence (IFAT). In addition, detection of amastigotes was performed by immunohistochemistry (IHC) in skin lesions of all cats. VL was diagnosed in 27/55 (49.1%) cats with dermatological problems. Amastigotes were found in lymphoid organs of 10/27 (37.0%) cats; serology of 14/27 (51.9%), 6/27 (22.2%) and 5/27 (18.5%) cats was positive for ELISA, IFAT and both, respectively. The IHC identified 9/27 (33.3%) cats; 5/27 (18.5%) were positive only for IHC and therefore increased the overall sensitivity. Specific FIV antibodies were found in 6/55(10.9%) cats, of which 5/6 (83.3%) had leishmaniosis. Real time PCR followed by amplicon sequencing successfully confirmed L chagasi infection. In conclusion, dermatological lesions in cats from endemic areas was highly associated to visceral leishmaniosis, and therefore skin IHC and differential diagnosis of LV should be always conducted in dermatological patients in such areas. (c) 2011 Elsevier B.V. All rights reserved. | en |
dc.description.sponsorship | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | - |
dc.format.extent | 22-28 | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier B.V. | - |
dc.source | Web of Science | - |
dc.subject | Feline leishmaniosis | en |
dc.subject | ELISA | en |
dc.subject | IFAT | en |
dc.subject | Immunohistochemical | en |
dc.subject | RT-PCR | en |
dc.title | Leishmania chagasi infection in cats with dermatologic lesions from an endemic area of visceral leishmaniosis in Brazil | en |
dc.type | outro | - |
dc.contributor.institution | Universidade Estadual Paulista (UNESP) | - |
dc.contributor.institution | Universidade de São Paulo (USP) | - |
dc.contributor.institution | Universidade Federal do Paraná (UFPR) | - |
dc.contributor.institution | IDEXX Labs Inc | - |
dc.description.affiliation | São Paulo State Univ, Dept Vet Clin Surg & Reprod, BR-16050680 São Paulo, Brazil | - |
dc.description.affiliation | São Paulo State Univ, Dept Anim Prod & Hlth, BR-16050680 São Paulo, Brazil | - |
dc.description.affiliation | Univ São Paulo, Dept Pathol, BR-01246903 São Paulo, Brazil | - |
dc.description.affiliation | Universidade Federal do Paraná (UFPR), Dept Vet Med, BR-80035050 Curitiba, Parana, Brazil | - |
dc.description.affiliation | IDEXX Labs Inc, W Sacramento, CA 95605 USA | - |
dc.description.affiliationUnesp | São Paulo State Univ, Dept Vet Clin Surg & Reprod, BR-16050680 São Paulo, Brazil | - |
dc.description.affiliationUnesp | São Paulo State Univ, Dept Anim Prod & Hlth, BR-16050680 São Paulo, Brazil | - |
dc.description.sponsorshipId | FAPESP: 09/52812-3 | - |
dc.identifier.doi | 10.1016/j.vetpar.2010.12.042 | - |
dc.identifier.wos | WOS:000291962200004 | - |
dc.rights.accessRights | Acesso restrito | - |
dc.relation.ispartof | Veterinary Parasitology | - |
Appears in Collections: | Artigos, TCCs, Teses e Dissertações da Unesp |
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