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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/42629
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dc.contributor.authorStorti-Melo, Luciane Moreno-
dc.contributor.authorCosta, Daniela Reis da-
dc.contributor.authorSouza-Neiras, Wanessa Christina-
dc.contributor.authorCassiano, Gustavo Capatti-
dc.contributor.authorD'Almeida Couto, Vanja Suely Calvosa-
dc.contributor.authorPovoa, Marinete Marins-
dc.contributor.authorSoares, Irene da Silva-
dc.contributor.authorCarvalho, Luzia Helena de-
dc.contributor.authorArevalo-Herrera, Myrian-
dc.contributor.authorHerrera, Socrates-
dc.contributor.authorBaptista Rossit, Andrea Regina-
dc.contributor.authorCordeiro, Jose Antonio-
dc.contributor.authorMattos, Luiz Carlos de-
dc.contributor.authorMachado, Ricardo Luiz Dantas-
dc.date.accessioned2014-05-20T15:34:42Z-
dc.date.accessioned2016-10-25T18:11:06Z-
dc.date.available2014-05-20T15:34:42Z-
dc.date.available2016-10-25T18:11:06Z-
dc.date.issued2012-02-01-
dc.identifierhttp://dx.doi.org/10.1016/j.actatropica.2011.10.009-
dc.identifier.citationActa Tropica. Amsterdam: Elsevier B.V., v. 121, n. 2, p. 152-155, 2012.-
dc.identifier.issn0001-706X-
dc.identifier.urihttp://hdl.handle.net/11449/42629-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/42629-
dc.description.abstractWe evaluated the influence of allelic frequency of the human leukocyte antigen (HLA) -DRB1 on the acquisition of antibody response against malaria sporozoite and merozoite peptides in patients with Plasmodium vivax malaria acquired in endemic areas of Brazil. IgG antibodies were detected by enzyme-linked immunosorbent assay against four peptides of circumsporozoite protein (CSP) (amino, carboxyl, and VK210 and VK247 repeats) and peptides of merozoite surface protein 1 (MSP-1), apical membrane antigen 1 (AMA-1), and Duffy-binding protein (DBP). We found an association between HLA-DR3 and HLA-DR5 alleles and lack of antibody response to CSP amino terminal, as well as an association between HILA-DR3 and the highest antibody response to MSP1 (Pv200L). In conclusion, we suggest a potential regulatory role of the H1A-DRB1 alleles in the production of antibodies to a conserved region of P. vivax CSP and MSP1 in Brazilian population exposed to malaria. (C) 2011 Elsevier B.V. All rights reserved.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.description.sponsorshipCOLCIENCIAS-
dc.description.sponsorshipMinistry of Social Protection-
dc.description.sponsorshipNational Institute of Allergy and Infectious Diseases (NIAID)-
dc.format.extent152-155-
dc.language.isoeng-
dc.publisherElsevier B.V.-
dc.sourceWeb of Science-
dc.subjectPlasmodium vivaxen
dc.subjectHLA-DRB1en
dc.subjectAntibody responseen
dc.titleInfluence of HLA-DRB-1 alleles on the production of antibody against CSP, MSP-1, AMA-1, and DBP in Brazilian individuals naturally infected with Plasmodium vivaxen
dc.typeoutro-
dc.contributor.institutionUniversidade Federal de Sergipe (UFS)-
dc.contributor.institutionFaculdade de Medicina de São José do Rio Preto (FAMERP)-
dc.contributor.institutionUniversidade Federal do Triângulo Mineiro (UFTM)-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionNucleo Estadual Amapa CRDT-
dc.contributor.institutionSecretaria Vigilancia Saude-
dc.contributor.institutionUniversidade de São Paulo (USP)-
dc.contributor.institutionFundação Oswaldo Cruz-
dc.contributor.institutionUniv Valle-
dc.contributor.institutionUniversidade Federal Fluminense (UFF)-
dc.description.affiliationUniv Fed Sergipe, Dept Biociencias, BR-49500000 Itabaiana, SE, Brazil-
dc.description.affiliationFaculdade de Medicina de São José do Rio Preto (FAMERP), Dept Doencas Dermatol Infecciosas & Parasitarias, Ctr Invest Microrganismos, BR-15090000 São Paulo, Brazil-
dc.description.affiliationUniv Fed Triangulo Mineiro, Inst Ciencias Exatas Nat & Educ, BR-38025180 Uberaba, MC, Brazil-
dc.description.affiliationUniv Estadual Paulista, BR-15054000 São Paulo, Brazil-
dc.description.affiliationNucleo Estadual Amapa CRDT, Minist Saude, BR-68900430 Macapa, Amapa, Brazil-
dc.description.affiliationSecretaria Vigilancia Saude, Inst Evandro Chagas, Lab Pesquisas Basicas Malaria, BR-6703000 Ananindeua, Para, Brazil-
dc.description.affiliationUniv São Paulo, Fac Ciencias Farmaceut, BR-05508900 São Paulo, Brazil-
dc.description.affiliationFundação Oswaldo Cruz, Ctr Pesquisas Rene Rachou, Lab Malaria, BR-30190002 Belo Horizonte, MG, Brazil-
dc.description.affiliationUniv Valle, Fac Salud, Inst Inmunol, Cali, Colombia-
dc.description.affiliationUniv Fed Fluminense, Inst Biomed, Dept Microbiol & Parasitol, BR-24210130 Rio de Janeiro, Brazil-
dc.description.affiliationFaculdade de Medicina de São José do Rio Preto (FAMERP), Dept Epidemiol, BR-15090000 São Paulo, Brazil-
dc.description.affiliationFaculdade de Medicina de São José do Rio Preto (FAMERP), Dept Biol Mol, Lab Imunohematol, BR-15090000 São Paulo, Brazil-
dc.description.affiliationUnespUniv Estadual Paulista, BR-15054000 São Paulo, Brazil-
dc.description.sponsorshipIdFAPESP: 02/09546-1-
dc.description.sponsorshipIdFAPESP: 06/09546-1-
dc.description.sponsorshipIdCNPq: 302353/03-8-
dc.description.sponsorshipIdCNPq: 410405/2006-0-
dc.description.sponsorshipIdCOLCIENCIAS: 1106-04-16489)-
dc.description.sponsorshipIdMinistry of Social Protection: 2304-04-19524-
dc.description.sponsorshipIdMinistry of Social Protection: 253-2005-
dc.description.sponsorshipIdNational Institute of Allergy and Infectious Diseases (NIAID): 49486/TMRC-
dc.identifier.doi10.1016/j.actatropica.2011.10.009-
dc.identifier.wosWOS:000300132800014-
dc.rights.accessRightsAcesso aberto-
dc.identifier.fileWOS000300132800014.pdf-
dc.relation.ispartofActa Tropica-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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