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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/63952
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dc.contributor.authorMendes-Giannini, Maria José Soares-
dc.contributor.authorBueno, J. P.-
dc.contributor.authorAparecida Shikanai-Yasuda, M.-
dc.contributor.authorFerreira, A. W.-
dc.contributor.authorMasuda, A.-
dc.date.accessioned2014-05-27T07:35:52Z-
dc.date.accessioned2016-10-25T18:12:24Z-
dc.date.available2014-05-27T07:35:52Z-
dc.date.available2016-10-25T18:12:24Z-
dc.date.issued1989-12-09-
dc.identifierhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC267138/-
dc.identifier.citationJournal of Clinical Microbiology, v. 27, n. 12, p. 2842-2845, 1989.-
dc.identifier.issn0095-1137-
dc.identifier.urihttp://hdl.handle.net/11449/63952-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/63952-
dc.description.abstractThe 43,000-molecular-weight (43K) soluble glycoprotein was detected in sera of patients with paracoccidioidomycosis by the immunoblot technique by using as the probe rabbit monospecific antisera to this fraction. The 43K antigen was present before treatment in sera of patients with the acute (juvenile) form; it started to disappear from circulation after 10 months of chemotherapy, and it was undetectable afer 2 years of treatment. In the chronic cases, the 43K antigen was detected in patients without treatment, and it was absent in the healed cases. The detection of the 43K protein specific to Paracoccidioides brasiliensis may be important for its diagnostic value as well as for modulation of the host immune response.en
dc.format.extent2842-2845-
dc.language.isoeng-
dc.sourceScopus-
dc.subjectfungus antigen-
dc.subjectglycoprotein-
dc.subjectimmunoglobulin g-
dc.subjectclinical article-
dc.subjectfungus-
dc.subjecthuman-
dc.subjecthuman cell-
dc.subjectimmunoblotting-
dc.subjectnonhuman-
dc.subjectparacoccidioides brasiliensis-
dc.subjectpriority journal-
dc.subjectserum-
dc.subjectsouth american blastomycosis-
dc.subjectAntigens, Fungal-
dc.subjectChromatography, Affinity-
dc.subjectElectrophoresis, Polyacrylamide Gel-
dc.subjectGlycoproteins-
dc.subjectHuman-
dc.subjectImmune Sera-
dc.subjectImmunoblotting-
dc.subjectMitosporic Fungi-
dc.subjectMolecular Weight-
dc.subjectParacoccidioides-
dc.subjectParacoccidioidomycosis-
dc.subjectSupport, Non-U.S. Gov't-
dc.subjectTime Factors-
dc.subjectFungi-
dc.subjectOryctolagus cuniculus-
dc.subjectParacoccidioides brasiliensis-
dc.titleDetection of the 43,000-molecular-weight glycoprotein in sera of patients with paracoccidioidomycosisen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationDep. de Analises Clinicas Fac. de Ciencias Farmaceut. UNESP, Araraquara-
dc.description.affiliationUnespDep. de Analises Clinicas Fac. de Ciencias Farmaceut. UNESP, Araraquara-
dc.rights.accessRightsAcesso aberto-
dc.identifier.file2-s2.0-0024354515.pdf-
dc.relation.ispartofJournal of Clinical Microbiology-
dc.identifier.scopus2-s2.0-0024354515-
dc.identifier.orcid0000-0002-8059-0826-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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