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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/64490
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dc.contributor.authorQueiroz-Neto, Antonio de-
dc.contributor.authorMataqueiro, Maria Isabel-
dc.contributor.authorSantana, Aureo Evangelista-
dc.contributor.authorAlessi, Antonio Carlos-
dc.date.accessioned2014-05-27T11:17:57Z-
dc.date.accessioned2016-10-25T18:13:20Z-
dc.date.available2014-05-27T11:17:57Z-
dc.date.available2016-10-25T18:13:20Z-
dc.date.issued1994-07-04-
dc.identifierhttp://dx.doi.org/10.1016/0378-8741(94)90115-5-
dc.identifier.citationJournal of Ethnopharmacology, v. 43, n. 1, p. 45-51, 1994.-
dc.identifier.issn0378-8741-
dc.identifier.urihttp://hdl.handle.net/11449/64490-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/64490-
dc.description.abstractThe extract prepared from dried seeds of Cucurbita maxima was administered to rats and pigs. Following a single dose or 4 weeks of daily oral administration, the extract produced no changes in serum glucose, urea, creatinine, total protein, uric acid, GOT, GPT, LDH or blood counts. Urine analysis (urea, uric acid, creatinine, total protein, Na and K), as well as histopathological investigation, showed no abnormalities. These results taken as a whole indicate that the seeds of C. maxima as used in Brazilian folk medicine are not toxic for rats and swine.en
dc.format.extent45-51-
dc.language.isoeng-
dc.sourceScopus-
dc.subjectCucurbita maxima-
dc.subjectPumpkin-
dc.subjectToxicity-
dc.subjectalanine aminotransferase-
dc.subjectaspartate aminotransferase-
dc.subjectcreatinine-
dc.subjectglucose-
dc.subjectlactate dehydrogenase-
dc.subjectplant extract-
dc.subjectprotein-
dc.subjecturea-
dc.subjecturic acid-
dc.subjectaminotransferase blood level-
dc.subjectanimal experiment-
dc.subjectanimal tissue-
dc.subjectblood cell count-
dc.subjectcontrolled study-
dc.subjectcreatinine blood level-
dc.subjectcreatinine urine level-
dc.subjectdrug safety-
dc.subjectfemale-
dc.subjectglucose blood level-
dc.subjectlactate dehydrogenase blood level-
dc.subjectnonhuman-
dc.subjectoral drug administration-
dc.subjectpotassium urine level-
dc.subjectprotein urine level-
dc.subjectrat-
dc.subjectsodium urine level-
dc.subjectswine-
dc.subjecttraditional medicine-
dc.subjecturea blood level-
dc.subjecturic acid blood level-
dc.subjecturic acid urine level-
dc.subjecturinalysis-
dc.subjectweight gain-
dc.subjectAdministration, Oral-
dc.subjectAnimal-
dc.subjectBlood Cell Count-
dc.subjectBlood Glucose-
dc.subjectBlood Proteins-
dc.subjectBrazil-
dc.subjectCreatinine-
dc.subjectDrug Evaluation, Preclinical-
dc.subjectElectrolytes-
dc.subjectFemale-
dc.subjectHeart-
dc.subjectKidney-
dc.subjectLiver-
dc.subjectLung-
dc.subjectPancreas-
dc.subjectPlant Extracts-
dc.subjectRandom Allocation-
dc.subjectRats-
dc.subjectRats, Wistar-
dc.subjectSeeds-
dc.subjectSpleen-
dc.subjectSupport, Non-U.S. Gov't-
dc.subjectSwine-
dc.subjectUrea-
dc.subjectUric Acid-
dc.titleToxicologic evaluation of acute and subacute oral administration of Cucurbita maxima seed extracts to rats and swineen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationDepartamento de Morfologia e Fisiologia Animal-
dc.description.affiliationDepartamento de Clinica e Cirurgia Veterinária-
dc.description.affiliationDepartamento de Patologia Veterinária Faculdade de Ciências Agrárias e Veterinárias de Jaboticabal, São Paulo-
dc.identifier.doi10.1016/0378-8741(94)90115-5-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofJournal of Ethnopharmacology-
dc.identifier.scopus2-s2.0-0028363013-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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