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dc.contributor.authorMontelli, Augusto Cezar-
dc.contributor.authorWatanabe, Dard S.A. Aoki-
dc.contributor.authorMichelin, Lourival Antônio-
dc.contributor.authorSadatsune, Terue-
dc.identifier.citationRevista Brasileira de Medicina, v. 53, n. 9, p. 963-969, 1996.-
dc.description.abstractSince 1988 to 1992, a study about susceptibility to antimicrobial drugs of bacterias isolated from hospitalized patients was performed. The compared susceptibility to important drugs (ampicilin, cephalothin, cefoxitin, ceftazidime, ceftriaxone, aztreonam, gentamicin, amikacin, peftoxacin, ciprofloxacin, imipenem, oxacillin and vancomicin) was investigated in 1200 strains (300 of each specie) of the prevalent bacterias: E. coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and S. aureus. Minimal inhibitory concentration (MIC) was determined by agar dilution method, using from 0,05 to 256 mcg of each drug per ml of culture medium (Mueller-Hinton). Ranges of MIC, MIC 50%, MIC 90% and the proportion of resistant strains were determined and permited to know the 4 drugs that were found to be more active against bacterias; the CIM 90% values are: E. coli - aztreonam (0,1 mcg/ml), pefloxacin (0,1), ceftazidime (0,25) and ceftriaxone (0,05); K. pneumoniae - aztreonam (0,25), ceftriaxone (0,25), ceftazidime (0,5) and pefloxacin (2,0); P. aeruginosa - imipenem (4,0), aztreonam (16), ceftazidime (16) and ciprofloxacin (16); S. aureus - vancomicina (1,0), ciprofloxacin (8,0), arnicacina (128) and cephalothin (128 mg/ml). The better in vitro antibacterial activity observed was related to: aztreonam (77-100% of the sensitive strains), ceftazidime (50-99,7%), pefloxacin (73-99,7%), ciprofloxacin(80%), imipenem (93%) and vancomicin (100%).en
dc.subjectAntimicrobial drugs-
dc.subjectBacterial sensitivity-
dc.subjectHospitalar infection-
dc.titleEstudo sobre a resistência aos antimicrobianos em bactérias isoladas de pacientes hospitalizados (Botucatu, 1988-1992)pt
dc.title.alternativeA survey of resistance to antimicrobial drugs in isolated bacterias from hospitalized patients (Botucatu, 1988-1992)en
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationDepartamento de Clínica Faculdade Med. de Botucatu - Unesp.-
dc.description.affiliationDepto. de Microbiologia e Imunologia Instituto de Biociéncias Campus de Botucatu - Unesp.-
dc.description.affiliationUnespDepartamento de Clínica Faculdade Med. de Botucatu - Unesp.-
dc.description.affiliationUnespDepto. de Microbiologia e Imunologia Instituto de Biociéncias Campus de Botucatu - Unesp.-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofRevista Brasileira de Medicina-
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