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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/64872
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dc.contributor.authorSaad, Wilson Abrão-
dc.contributor.authorCamargo, Gabriela Pavan de Arruda-
dc.contributor.authorCamargo, Luiz Antonio de Arruda-
dc.date.accessioned2014-05-27T11:18:07Z-
dc.date.accessioned2016-10-25T18:14:02Z-
dc.date.available2014-05-27T11:18:07Z-
dc.date.available2016-10-25T18:14:02Z-
dc.date.issued1996-11-01-
dc.identifierhttp://dx.doi.org/10.1159/000139440-
dc.identifier.citationPharmacology. Basel: Karger, v. 53, n. 5, p. 281-288, 1996.-
dc.identifier.issn0031-7012-
dc.identifier.urihttp://hdl.handle.net/11449/64872-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/64872-
dc.description.abstractThe effects of clonidine on sodium and potassium excretions were examined after previous administration of prazosin (an α 1-adrenergic receptor antagonist) and yohimbine (an α 2-adrenergic receptor antagonist) into the ventromedial nucleus of the hypothalamus of conscious rats. Clonidine injected into the ventromedial nucleus of the hypothalamus induced inhibitory and facilitatory effects on the urinary sodium and potassium excretions. The results suggest that facilitatory effects of clonidine on natriuresis and kaliuresis are mediated through activation of α 1-adrenoceptors and that inhibitory effects require α(2A)-adrenoceptors.en
dc.format.extent281-288-
dc.language.isoeng-
dc.sourceScopus-
dc.subjectClonidine-
dc.subjectPotassium excretion-
dc.subjectPrazosin-
dc.subjectSodium excretion-
dc.subjectVentromedical nucleus, hypothalamus-
dc.subjectYohimbine-
dc.subjectalpha 1 adrenergic receptor-
dc.subjectalpha 2A adrenergic receptor-
dc.subjectalpha adrenergic receptor stimulating agent-
dc.subjectclonidine-
dc.subjectpotassium ion-
dc.subjectprazosin-
dc.subjectsodium ion-
dc.subjectyohimbine-
dc.subjectanimal experiment-
dc.subjectcontrolled study-
dc.subjectintracerebral drug administration-
dc.subjectkaliuresis-
dc.subjectmale-
dc.subjectnatriuresis-
dc.subjectnonhuman-
dc.subjectpotassium urine level-
dc.subjectpriority journal-
dc.subjectrat-
dc.subjectsodium urine level-
dc.subjectstimulation-
dc.subjectthalamus ventral nucleus-
dc.subjectAdrenergic alpha-Antagonists-
dc.subjectAnimals-
dc.subjectDose-Response Relationship, Drug-
dc.subjectHypothalamus-
dc.subjectKidney-
dc.subjectMale-
dc.subjectPotassium-
dc.subjectRats-
dc.subjectSodium-
dc.titleOn a dual role for clonidine stimulation of the ventromedial nucleus of the hypothalamus in sodium and potassium renal excretions of ratsen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationDepartment of Physiology School of Dentistry Paulista State University, Araraquara-
dc.description.affiliationDepartment of Physiology Paulista State University, 1680 Humaitá Street, Araraquara, SP 14801-903-
dc.description.affiliationUnespDepartment of Physiology School of Dentistry Paulista State University, Araraquara-
dc.description.affiliationUnespDepartment of Physiology Paulista State University, 1680 Humaitá Street, Araraquara, SP 14801-903-
dc.identifier.doi10.1159/000139440-
dc.identifier.wosWOS:A1996VY81500002-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofPharmacology-
dc.identifier.scopus2-s2.0-10544222836-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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