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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/65254
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dc.contributor.authorDa Graça Sgarbi, Diana Bridon-
dc.contributor.authorDa Silva, Antonio Jorge Ribeiro-
dc.contributor.authorCarlos, Iracilda Zeppone-
dc.contributor.authorSilva, Célio Lopes-
dc.contributor.authorAngluster, Jayme-
dc.contributor.authorAlviano, Celuta Sales-
dc.date.accessioned2014-05-27T11:18:17Z-
dc.date.accessioned2016-10-25T18:14:44Z-
dc.date.available2014-05-27T11:18:17Z-
dc.date.available2016-10-25T18:14:44Z-
dc.date.issued1997-12-01-
dc.identifierhttp://dx.doi.org/10.1023/A:1006803832164-
dc.identifier.citationMycopathologia, v. 139, n. 1, p. 9-14, 1997.-
dc.identifier.issn0301-486X-
dc.identifier.urihttp://hdl.handle.net/11449/65254-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/65254-
dc.description.abstractErgosterol peroxide, a presumed product of the H2O2-dependent enzymatic oxidation of ergosterol, has been isolated from yeast from yeast forms of the pathogenic fungus Sporothrix schenckii. The substance, which may have a role in fungal virulence, has been characterized mainly using spectroscopic methods (1H and 13C nuclear magnetic resonance and high resolution mass spectra). The purified compound showed a molecular formula of C28H44O3, displaying characteristic features of epidioxy sterols and was reverted to ergosterol when submitted to S. schenckii enzymatic extract.en
dc.format.extent9-14-
dc.language.isoeng-
dc.sourceScopus-
dc.subjectEpidioxy sterol-
dc.subjectReactive oxygen species-
dc.subjectSporothrix schenckii-
dc.subjectantineoplastic agent-
dc.subjectdrug derivative-
dc.subjectergosterol-
dc.subjectergosterol 5,8 peroxide-
dc.subjectergosterol-5,8-peroxide-
dc.subjectchemistry-
dc.subjectisolation and purification-
dc.subjectmetabolism-
dc.subjectnuclear magnetic resonance spectroscopy-
dc.subjectSporothrix-
dc.subjectthin layer chromatography-
dc.subjectAntineoplastic Agents-
dc.subjectChromatography, Thin Layer-
dc.subjectErgosterol-
dc.subjectMagnetic Resonance Spectroscopy-
dc.subjectFungi-
dc.titleIsolation of ergosterol peroxide and its reversion to ergosterol in the pathogenic fungus Sporothrix schenckiien
dc.typeoutro-
dc.contributor.institutionUniversidade Federal Fluminense (UFF)-
dc.contributor.institutionUniversidade Federal do Rio de Janeiro (UFRJ)-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionUniversidade de São Paulo (USP)-
dc.contributor.institutionCidade Universitária-
dc.description.affiliationDepto. de Microbiol. e Parasitologia Instituto Biomédico Universidade Federal Fluminense, Niterói, RJ-
dc.description.affiliationNucleo de Pesq. em Produtos Naturais Univ. Federal do Rio de Janeiro, RJ-
dc.description.affiliationDepto. de Análises Clinicas Faculdade Cie. Farmaceuticas A. Univ. Paulista Julio Mesquita Filho, Araraquara, SP-
dc.description.affiliationDepto. Parasitol., Microbiol. I. Esc. de Med. de Ribeirão Preto Universidade de São Paulo, Ribeirão Preto, SP e-
dc.description.affiliationInstituto de Microbiologia Univ. Federal do Rio de Janeiro, RJ-
dc.description.affiliationDepartamento de Microbiologia Geral Instituto de Microbiologia Cidade Universitária, Ilha do Fundão 21941-590, Rio de Janeiro, RJ-
dc.description.affiliationUnespDepto. de Análises Clinicas Faculdade Cie. Farmaceuticas A. Univ. Paulista Julio Mesquita Filho, Araraquara, SP-
dc.identifier.doi10.1023/A:1006803832164-
dc.identifier.wosWOS:000072341100002-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofMycopathologia-
dc.identifier.scopus2-s2.0-0031413998-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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