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dc.contributor.authorRocha, Noeme Sousa-
dc.contributor.authorBarbisan, Luis Fernando-
dc.contributor.authorDe Oliveira, Maria Luiza Cotrim-
dc.contributor.authorDe Camargo, Joo Lauro Viana-
dc.date.accessioned2014-05-27T11:20:25Z-
dc.date.accessioned2016-10-25T18:17:43Z-
dc.date.available2014-05-27T11:20:25Z-
dc.date.available2016-10-25T18:17:43Z-
dc.date.issued2002-03-06-
dc.identifierhttp://dx.doi.org/10.1002/tcm.10008-
dc.identifier.citationTeratogenesis Carcinogenesis and Mutagenesis, v. 22, n. 2, p. 103-111, 2002.-
dc.identifier.issn0270-3211-
dc.identifier.urihttp://hdl.handle.net/11449/66850-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/66850-
dc.description.abstractAqueous extracts of the sporophores of eight mushroom species were assessed for their ability to prevent H2O2-induced oxidative damage to cellular DNA using the single-cell gel electrophoresis (Comet) assay. The highest genoprotective effects were obtained with cold (20°C) and hot (100°C) water extracts of Agaricus bisporus and Ganoderma lucidum fruit bodies, respectively. No protective effects were observed with Mushroom Derived Preparations (MDPs) from Flammulina velutipes, Auricularia auricula, Hypsizygus marmoreus, Lentinula edodes, Pleurotus sajor-caju, and Volvariella volvacea. These findings indicate that some edible mushrooms represent a valuable source of biologically active compounds with potential for protecting cellular DNA from oxidative damage. © 2002 Wiley-Liss, Inc.en
dc.format.extent103-111-
dc.language.isoeng-
dc.sourceScopus-
dc.subjectAgaricus bisporus-
dc.subjectAnti-oxidants-
dc.subjectComet assay-
dc.subjectGanoderrna lucidum-
dc.subjectReactive oxygen species-
dc.subjectagaricus bisporus extract-
dc.subjectAuricularia auricula extract-
dc.subjectflammulina velutipes extract-
dc.subjectGanoderma lucidum extract-
dc.subjecthydrogen peroxide-
dc.subjecthypsizygus mormoreus extract-
dc.subjectlentinuloa edodes extract-
dc.subjectleurotus sajor caju extract-
dc.subjectmushroom derivative preparation-
dc.subjectmushroom extract-
dc.subjectplant extract-
dc.subjectunclassified drug-
dc.subjectvolvariella volvacea extract-
dc.subjectantioxidant activity-
dc.subjectDNA damage-
dc.subjectgel electrophoresis-
dc.subjectHong Kong-
dc.subjecthuman-
dc.subjecthuman cell-
dc.subjectmushroom-
dc.subjectmutagenesis-
dc.subjectoxidative stress-
dc.subjectpriority journal-
dc.subjectAgaricales-
dc.subjectComet Assay-
dc.subjectDNA Damage-
dc.subjectDNA, Neoplasm-
dc.subjectFungal Proteins-
dc.subjectHydrogen Peroxide-
dc.subjectMutagenicity Tests-
dc.subjectOxidation-Reduction-
dc.subjectOxidative Stress-
dc.subjectReactive Oxygen Species-
dc.subjectTumor Cells, Cultured-
dc.subjectAgaricus-
dc.subjectAuricula-
dc.subjectAuricularia auricula-judae-
dc.subjectBasidiomycota-
dc.subjectFlammulina-
dc.subjectFlammulina velutipes-
dc.subjectGanoderma-
dc.subjectGanoderma lucidum-
dc.subjectHypsizygus-
dc.subjectHypsizygus marmoreus-
dc.subjectLentinula-
dc.subjectLentinula edodes-
dc.subjectPleurotus-
dc.subjectPleurotus sajor-caju-
dc.subjectVolvariella volvacea-
dc.titleMushroom-derived preparations in the prevention of H2O2-induced oxidative damage to cellular DNAen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationDepartamento de Clnica Veterinria Faculdade de Medicina Veterinria e Zootecnia UNESP, Botucatu-
dc.description.affiliationDepartamento de Morfologia Instituto de Biologia UNESP, Botucatu-
dc.description.affiliationDepartamento de Patologia Faculdade de Medicina UNESP, Botucatu-
dc.description.affiliationDepartamento de Patologia Faculdade de Medicina Universidade Estadual Paulista (UNESP), Botucatu, 18618-000, SP-
dc.description.affiliationUnespDepartamento de Clnica Veterinria Faculdade de Medicina Veterinria e Zootecnia UNESP, Botucatu-
dc.description.affiliationUnespDepartamento de Morfologia Instituto de Biologia UNESP, Botucatu-
dc.description.affiliationUnespDepartamento de Patologia Faculdade de Medicina UNESP, Botucatu-
dc.description.affiliationUnespDepartamento de Patologia Faculdade de Medicina Universidade Estadual Paulista (UNESP), Botucatu, 18618-000, SP-
dc.identifier.doi10.1002/tcm.10008-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofTeratogenesis Carcinogenesis and Mutagenesis-
dc.identifier.scopus2-s2.0-0036179148-
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