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dc.contributor.authorRizzatti-Barbosa, Célia M.-
dc.contributor.authorNogueira, Mariana T. P.-
dc.contributor.authorDe Andrade, Eduardo D.-
dc.contributor.authorAmbrosano, Gláucia M. B.-
dc.contributor.authorDe Albergaria Barbosa, José R.-
dc.identifier.citationCranio, v. 21, n. 3, p. 221-225, 2003.-
dc.description.abstractTemporomandibular disorder (TMD) is characterized by a combination of symptoms affecting the temporomandibular joint and/or chewing muscles. The two most common clinical TMD symptoms are pain and dysfunction. Pain is usually caused by dysfunction, and emergency therapy has focused on controlling it. Recent investigations into TMD have led to the recommendation of antidepressants as a supporting treatment against constant neuralgic pain. The aim of this double-blind study was to verify the efficiency of antidepressants (amitriptyline) as a support in the treatment of chronic TMD pain. Twelve female volunteers presenting chronic TMD pain were divided into two groups and treated for 14 days: Group 1 with 25 mg/day of amitriptyline and Group 2 with a placebo. The intensity of pain and discomfort was evaluated daily, using a visual analog scale (VAS), over a period of seven days preceding the treatment (baseline), during the 14-day treatment, and for seven days after the treatment. The results revealed a significant reduction of pain and discomfort in Group 1 (75%) compared to Group 2 (28%) during the three weeks beginning at baseline (p< 0.01). Amitriptyline proved to be an efficient alternative treatment for chronic pain in TMD patients. Copyright © 2003 by CHROMA, Inc.en
dc.subjectantidepressant agent-
dc.subjecttricyclic antidepressant agent-
dc.subjectchronic pain-
dc.subjectclinical article-
dc.subjectclinical trial-
dc.subjectcomparative study-
dc.subjectcontrolled clinical trial-
dc.subjectcontrolled study-
dc.subjectdouble blind procedure-
dc.subjectdrug efficacy-
dc.subjectpain assessment-
dc.subjecttemporomandibular joint disorder-
dc.subjecttreatment outcome-
dc.subjectvisual analog scale-
dc.subjectchronic disease-
dc.subjectface pain-
dc.subjectrandomized controlled trial-
dc.subjectAntidepressive Agents, Tricyclic-
dc.subjectChronic Disease-
dc.subjectDouble-Blind Method-
dc.subjectFacial Pain-
dc.subjectPain Measurement-
dc.subjectTemporomandibular Joint Disorders-
dc.subjectTreatment Outcome-
dc.titleClinical evaluation of amitriptyline for the control of chronic pain caused by temporomandibular joint disordersen
dc.contributor.institutionDepto. de Protese e Periodontia-
dc.contributor.institutionUniversidade de São Paulo (USP)-
dc.contributor.institutionIntl. Assoc. for the Study of Pain-
dc.contributor.institutionIntl. Assoc. for Dental Research-
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)-
dc.contributor.institutionIntl. Assoc. for Dental Researchers-
dc.contributor.institutionDental School of Piracicaba-
dc.contributor.institutionBrazilian Soc. for Dental Research-
dc.contributor.institutionInternational Biometric Society-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionA. C. Camargo Cancer Center-
dc.description.affiliationDepto. de Protese e Periodontia, Av. Limeira, 901, CEP 13.414-018 Piracicaba, SP-
dc.description.affiliationState University of São Paulo-
dc.description.affiliationIntl. Assoc. for the Study of Pain-
dc.description.affiliationIntl. Assoc. for Dental Research-
dc.description.affiliationState University of Campinas-
dc.description.affiliationDept. of Prosthesis and Periodontol. Unicamp-
dc.description.affiliationIntl. Assoc. for Dental Researchers-
dc.description.affiliationDepartment of Physiological Sciences State University of Campinas-
dc.description.affiliationPharmacology Laboratory Dental School of Piracicaba-
dc.description.affiliationBrazilian Soc. for Dental Research-
dc.description.affiliationInternational Biometric Society-
dc.description.affiliationJulio Mesquita Filho State U.-
dc.description.affiliationA.C. Camargo Hospital, São Paulo-
dc.description.affiliationDepartment of Oral Medicine UNICAMP-
dc.description.affiliationDental Clinic UNICAMP Dental College-
dc.description.affiliationUnespJulio Mesquita Filho State U.-
dc.rights.accessRightsAcesso restrito-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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