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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/67460
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dc.contributor.authorFioretto, José Roberto-
dc.date.accessioned2014-05-27T11:20:55Z-
dc.date.accessioned2016-10-25T18:18:59Z-
dc.date.available2014-05-27T11:20:55Z-
dc.date.available2016-10-25T18:18:59Z-
dc.date.issued2003-11-01-
dc.identifierhttp://dx.doi.org/10.1590/S0021-75572003000800007-
dc.identifier.citationJornal de Pediatria, v. 79, n. SUPPL. 2, 2003.-
dc.identifier.issn0021-7557-
dc.identifier.urihttp://hdl.handle.net/11449/67460-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/67460-
dc.description.abstractObjective: To review the literature on inhaled nitric oxide and to describe its main clinical applications in pediatrics. Sources of data: A 10 year literature review with selection of the most important publications on inhaled nitric oxide, using the Medline and Cochrane Systematic Review databases. Summary of the findings: This review was organized as follows: introduction; metabolism and biological effects; clinical applications; dosage, gas administration and weaning; precautions and side-effects. Inhaled nitric oxide use was described in persistent pulmonary hypertension and hypoxia of the newborn, acute respiratory distress syndrome, primary pulmonary hypertension, heart surgery, chronic obstructive pulmonary disease, sickle cell anemia, and bronchospastic disease. Conclusions: Inhaled nitric oxide is a therapeutic approach with wide clinical applications in pediatrics. Its use is safe when administered in pediatric intensive care units under strict monitoring. As a pulmonary vasodilator, nitric oxide has beneficial effects on gas exchange and ventilation. Controlled trials, focusing on early gas administration should be performed under many clinical conditions, especially acute respiratory distress syndrome.en
dc.language.isopor-
dc.sourceScopus-
dc.subjectInhaled nitric oxide-
dc.subjectMechanical ventilation-
dc.subjectPediatrics-
dc.subjectPulmonary hypertension-
dc.subjectcorticosteroid-
dc.subjectdobutamine-
dc.subjectdopamine-
dc.subjectnitric oxide-
dc.subjectsurfactant-
dc.subjectbronchospasm-
dc.subjectchronic obstructive lung disease-
dc.subjectcongenital heart disease-
dc.subjectdata analysis-
dc.subjectdrug effect-
dc.subjectdrug mechanism-
dc.subjectdrug metabolism-
dc.subjectdrug safety-
dc.subjectdrug screening-
dc.subjectdrug utilization-
dc.subjectheart surgery-
dc.subjectheart transplantation-
dc.subjecthuman-
dc.subjectinhalation-
dc.subjectmedical information-
dc.subjectmethemoglobinemia-
dc.subjectnewborn hypoxia-
dc.subjectpulmonary hypertension-
dc.subjectrespiratory distress syndrome-
dc.subjectreview-
dc.subjectsickle cell anemia-
dc.subjectside effect-
dc.subjecttreatment contraindication-
dc.subjecttreatment indication-
dc.subjectweaning-
dc.subjectAdministration, Inhalation-
dc.subjectChild-
dc.subjectChild, Preschool-
dc.subjectHumans-
dc.subjectInfant-
dc.subjectInfant, Newborn-
dc.subjectIntensive Care-
dc.subjectLung Diseases-
dc.subjectNitric Oxide-
dc.subjectVasodilator Agents-
dc.titleUso do óxido nítrico em pediatriapt
dc.title.alternativeInhaled nitric oxide in pediatricsen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationUNESP Faculdade de Medicina de Botucatu Dep. Pediatria, CEP 18618-970 - Botucatu - SP-
dc.description.affiliationUnespUNESP Faculdade de Medicina de Botucatu Dep. Pediatria, CEP 18618-970 - Botucatu - SP-
dc.identifier.doi10.1590/S0021-75572003000800007-
dc.identifier.scieloS0021-75572003000800007-
dc.rights.accessRightsAcesso aberto-
dc.identifier.file2-s2.0-0348225443.pdf-
dc.relation.ispartofJornal de Pediatria-
dc.identifier.scopus2-s2.0-0348225443-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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