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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/67471
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dc.contributor.authorFelippe de Souza, J. A M-
dc.contributor.authorCaetano, M. A L-
dc.contributor.authorYoneyama, Takashi-
dc.date.accessioned2014-05-27T11:20:56Z-
dc.date.accessioned2016-10-25T18:19:00Z-
dc.date.available2014-05-27T11:20:56Z-
dc.date.available2016-10-25T18:19:00Z-
dc.date.issued2003-11-07-
dc.identifierhttp://dx.doi.org/10.1109/ACC.2003.1239749-
dc.identifier.citationProceedings of the American Control Conference, v. 2, p. 1188-1193.-
dc.identifier.issn0743-1619-
dc.identifier.urihttp://hdl.handle.net/11449/67471-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/67471-
dc.description.abstractHere the results for CD4+T cells count and the viral load obtained from HIV sero-positive patients are compared with results from numerical simulations by computer. Also, the standard scheme of administration of drugs anti HIV (HAART schemes) which uses constant doses is compared with an alternative sub-optimal teatment scheme which uses variable drug dosage according to the evolution of a quantitative measure of the side effects. The quantitative analysis done here shows that it is possible to obtain, using the alternative scheme, the same performance of actual data but using variable dosage and having fewer side effects. Optimal control theory is used to solve and also to provide a prognosis related to the strategies for control of viraemia.en
dc.format.extent1188-1193-
dc.language.isoeng-
dc.sourceScopus-
dc.subjectAIDS-
dc.subjectDirect method-
dc.subjectOptimization-
dc.subjectTreatment-
dc.subjectComputer simulation-
dc.subjectDrug dosage-
dc.subjectPatient treatment-
dc.subjectProblem solving-
dc.subjectViruses-
dc.subjectSub-optimal scheme-
dc.subjectControl theory-
dc.titleAnalysis of a sub-optimal scheme of drug dosage in the AIDS treatmenten
dc.typeoutro-
dc.contributor.institutionUniversidade da Beira Interior-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionInst. Tecn. de Aeronáutica-
dc.description.affiliationUniversidade da Beira Interior, Covilhã-
dc.description.affiliationUniversidade Estadual Paulista IGCE, Rio Claro-
dc.description.affiliationInst. Tecn. de Aeronáutica, São José dos Campos-
dc.description.affiliationUnespUniversidade Estadual Paulista IGCE, Rio Claro-
dc.identifier.doi10.1109/ACC.2003.1239749-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofProceedings of the American Control Conference-
dc.identifier.scopus2-s2.0-0142169391-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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