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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/68495
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dc.contributor.authorPelizon, A. C.-
dc.contributor.authorKaneno, Ramon-
dc.contributor.authorSoares, A. M V C-
dc.contributor.authorMeira, D. A.-
dc.contributor.authorSartori, A.-
dc.date.accessioned2014-05-27T11:21:40Z-
dc.date.accessioned2016-10-25T18:21:19Z-
dc.date.available2014-05-27T11:21:40Z-
dc.date.available2016-10-25T18:21:19Z-
dc.date.issued2005-11-16-
dc.identifierhttp://www.biomed.cas.cz/physiolres/2005/issue5/pelizon.htm-
dc.identifier.citationPhysiological Research, v. 54, n. 5, p. 557-564, 2005.-
dc.identifier.issn0862-8408-
dc.identifier.urihttp://hdl.handle.net/11449/68495-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/68495-
dc.description.abstractIn this study we investigated the effect of β-glucan derived from Saccharomyces cerevisiae on fungicidal activity, cytokine production and natural killer activity. Spleen and peritoneal cells from female C57BL/6 mice, previously injected (24 or 48 h) with 20 or 100 μg of glucan by i.p. route, were assayed. In vivo β-glucan administration primed spleen cells for a higher production of IL-12 and TNF-α when S. aureus was used as a stimulus. In addition, β-glucan increased NK spleen cells activity against YAC target cells. Some immunomodulatory activities not yet described for β-glucan were observed in this work. © 2005 Institute of Physiology, Academy of Sciences of the Czech Republic.en
dc.format.extent557-564-
dc.language.isoeng-
dc.sourceScopus-
dc.subjectβ-glucan-
dc.subjectFungicidal activity-
dc.subjectIL-12-
dc.subjectNK activity-
dc.subjectTNF-α-
dc.subjectbeta glucan-
dc.subjectinterleukin 12-
dc.subjecttumor necrosis factor alpha-
dc.subjectanimal cell-
dc.subjectanimal experiment-
dc.subjectcell activity-
dc.subjectcontrolled study-
dc.subjectcytokine production-
dc.subjectdrug effect-
dc.subjectfemale-
dc.subjectfungicidal activity-
dc.subjectimmunomodulation-
dc.subjectmouse-
dc.subjectnatural killer cell-
dc.subjectnonhuman-
dc.subjectperitoneum cell-
dc.subjectSaccharomyces cerevisiae-
dc.subjectspleen cell-
dc.subjecttarget cell-
dc.subjectAnimals-
dc.subjectAntifungal Agents-
dc.subjectbeta-Glucans-
dc.subjectCytokines-
dc.subjectDose-Response Relationship, Drug-
dc.subjectFemale-
dc.subjectImmunologic Factors-
dc.subjectKiller Cells, Natural-
dc.subjectMice-
dc.subjectMice, Inbred C57BL-
dc.subjectParacoccidioides-
dc.titleImmunomodulatory activities associated with β-glucan derived from Saccharomyces cerevisiaeen
dc.typeoutro-
dc.contributor.institutionUniversidade de São Paulo (USP)-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationDepartment of Microbiology and Immunology Institute de Biosciences State University of Sao Paulo, Sao Paulo-
dc.description.affiliationDepartment of Tropical Diseases and Diagnosis by Image Faculty of Medicine State University of Sao Paulo, Sao Paulo-
dc.description.affiliationDepartment of Microbiology and Immunology Instituto de Biociências Universidade Estadual Paulista (UNESP)-
dc.description.affiliationUnespDepartment of Microbiology and Immunology Instituto de Biociências Universidade Estadual Paulista (UNESP)-
dc.rights.accessRightsAcesso aberto-
dc.identifier.file2-s2.0-27644525584.pdf-
dc.relation.ispartofPhysiological Research-
dc.identifier.scopus2-s2.0-27644525584-
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