You are in the accessibility menu

Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorBrandi, Jamile-
dc.contributor.authorOliveira, Eder C.-
dc.contributor.authorMonteiro, Nilson K.-
dc.contributor.authorVasconcelos, Ana Flora D.-
dc.contributor.authorDekker, Robert F. H.-
dc.contributor.authorBarbosa, Aneli M.-
dc.contributor.authorSilveira, Joana L. M.-
dc.contributor.authorMourao, Paulo A. S.-
dc.contributor.authorCorradi da Silva, Maria de Lourdes-
dc.identifier.citationJournal of Microbiology and Biotechnology. Seoul: Korean Soc Microbiology & Biotechnology, v. 21, n. 10, p. 1036-1042, 2011.-
dc.description.abstractThe exopolysaccharide botryosphaeran (EPS(GLC); a (1 -> 3)(1 -> 6)-beta-D-glucan from Botryosphaeria rhodina MAMB-05) was sulfonated to produce a water-soluble fraction (EPS(GLC)-S) using pyridine and chlorosulfonic acid in formamid. This procedure was then repeated twice to produce another fraction (EPS(GLC)-RS) with a higher degree of substitution (DS, 1.64). The purity of each botryosphaeran sample (unsulfonated and sulfonated) was assessed by gel filtration chromatography (Sepharose CL-4B), where each polysaccharide was eluted as a single symmetrical peak. The structures of the sulfonated and re-sulfonated botryosphaerans were investigated using ultraviolet-visible (UV-Vis), Fourier-transform infrared (FT-IR), and (13)C nuclear magnetic resonance ((13)C NMR) spectroscopies. EPS(GLC) and EPS(GLC)-RS were also assayed for anticoagulation activity, and EPS(GLC)-RS was identified as an anticoagulant.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.description.sponsorshipFundação Araucária de Apoio ao Desenvolvimento Científico e Tecnológico do Paraná (FAADCT/PR)-
dc.description.sponsorshipPrograma de Apoio aos Núcleos de Excelência (PRONEX)-
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.publisherKorean Soc Microbiology & Biotechnology-
dc.sourceWeb of Science-
dc.subjectanticoagulant activityen
dc.subjectBotryosphaeria rhodina MAMB-05en
dc.titleChemical Modification of Botryosphaeran: Structural Characterization and Anticoagulant Activity of a Water-Soluble Sulfonated (1 -> 3)(1 -> 6)-beta-D-Glucanen
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionLakehead Univ-
dc.contributor.institutionUniversidade Estadual de Londrina (UEL)-
dc.contributor.institutionUniversidade Federal do Paraná (UFPR)-
dc.contributor.institutionUniversidade Federal do Rio de Janeiro (UFRJ)-
dc.description.affiliationUniv Estadual Paulista, Fac Ciencias & Technol, Dept Fis Quim Biol, BR-19060900 Presidente Prudente, SP, Brazil-
dc.description.affiliationLakehead Univ, Biorefining Res Inst, Thunder Bay, on P7B 5E1, Canada-
dc.description.affiliationUniversidade Estadual de Londrina (UEL), Dept Bioquim & Biotechnol, BR-86051990 Londrina, Parana, Brazil-
dc.description.affiliationUniversidade Federal do Paraná (UFPR), Dept Bioquim & Biol Mol, BR-81531980 Curitiba, Parana, Brazil-
dc.description.affiliationUniv Fed Rio de Janeiro, HU Clementino Fraga Filho, Lab Tecido Conjunt, BR-21941590 Rio de Janeiro, Brazil-
dc.description.affiliationUnespUniv Estadual Paulista, Fac Ciencias & Technol, Dept Fis Quim Biol, BR-19060900 Presidente Prudente, SP, Brazil-
dc.description.sponsorshipIdFAPESP: 05/53879-3-
dc.description.sponsorshipIdFAPESP: 05/50936-6-
dc.description.sponsorshipIdFundação Araucaria: 5777-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofJournal of Microbiology and Biotechnology-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.