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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/69901
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dc.contributor.authorMelo de Mendonça, Adriano Augusto-
dc.contributor.authorChaves Souza, Pedro Paulo-
dc.contributor.authorHebling, Josimeri-
dc.contributor.authorde Souza Costa, Carlos Alberto-
dc.date.accessioned2014-05-27T11:22:36Z-
dc.date.accessioned2016-10-25T18:24:22Z-
dc.date.available2014-05-27T11:22:36Z-
dc.date.available2016-10-25T18:24:22Z-
dc.date.issued2007-10-01-
dc.identifierhttp://dx.doi.org/10.1016/j.tripleo.2007.05.017-
dc.identifier.citationOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology, v. 104, n. 4, 2007.-
dc.identifier.issn1079-2104-
dc.identifier.urihttp://hdl.handle.net/11449/69901-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/69901-
dc.description.abstractObjective: The present study evaluated the cytotoxic effects of hard setting applied on the odontoblastlike cells MDPC-23. Study design: Eighty round-shaped samples were prepared with the following experimental materials: calcium hydroxide, Vitrebond, RelyX Luting, and RelyX Unicem. The samples were placed in serum-free culture medium and incubated for 24 hours or 7 days at 37°C with 5% CO 2 and 95% air. The odontoblast cells were plated in the wells and incubated for 72 hours. After this period, the complete culture medium was replaced by the extracts obtained from every sample, and the methyltetrazolium assay was carried out to evaluate the cell metabolism. Results: For the 24-hour period, the experimental materials calcium hydroxide, Vitrebond, RelyX Luting, and RelyX Unicem decreased the cell metabolic activity by 91.52%, 81.14%, 78.17%, and 2.64%, respectively. For the 7-day period, calcium hydroxide, Vitrebond, RelyX Luting, and RelyX Unicem decreased the metabolic activity of the MDPC-23 cells by 91.13%, 87.27%, 79.04%, and 10.51%, respectively. Conclusion: RelyX Unicem presented the lowest cytopathic effects to the cultured odontoblast cell line. © 2007 Mosby, Inc. All rights reserved.en
dc.language.isoeng-
dc.sourceScopus-
dc.subjectglass ionomer-
dc.subjectresin cement-
dc.subjectroot canal filling material-
dc.subjectcell line-
dc.subjectdrug effect-
dc.subjecthuman-
dc.subjectodontoblast-
dc.subjectCell Line, Transformed-
dc.subjectGlass Ionomer Cements-
dc.subjectHumans-
dc.subjectOdontoblasts-
dc.subjectResin Cements-
dc.subjectRoot Canal Filling Materials-
dc.titleCytotoxic effects of hard-setting cements applied on the odontoblast cell line MDPC-23en
dc.typeoutro-
dc.contributor.institutionUniversidade de São Paulo (USP)-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationDepartment of Restorative Dentistry School of Dentistry University of São Paulo State, Araraquara, São Paulo-
dc.description.affiliationDepartment of Biochemistry and Immunology Medical School University of São Paulo, Ribeirao Preto, Sao Paulo-
dc.description.affiliationDepartment of Orthodontics and Pediatric Dentistry School of Dentistry University of São Paulo State, Araraquara, São Paulo-
dc.description.affiliationDepartment of Physiology and Pathology School of Dentistry University of São Paulo State, Araraquara, São Paulo-
dc.identifier.doi10.1016/j.tripleo.2007.05.017-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology-
dc.identifier.scopus2-s2.0-34648834418-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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