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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/70520
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dc.contributor.authorVieira, Evanice Menezes Marçal-
dc.contributor.authorUeno, Camila Satie Ferreira-
dc.contributor.authorValva, Vivian Neves-
dc.contributor.authorGoulart, Maria das Graças Vilela-
dc.contributor.authorNogueira, Terezinha de Oliveira-
dc.contributor.authorGomes, Mônica Fernandes-
dc.date.accessioned2014-05-27T11:23:38Z-
dc.date.accessioned2016-10-25T18:25:50Z-
dc.date.available2014-05-27T11:23:38Z-
dc.date.available2016-10-25T18:25:50Z-
dc.date.issued2008-08-04-
dc.identifierhttp://dx.doi.org/10.1590/S1806-83242008000200015-
dc.identifier.citationBrazilian Oral Research, v. 22, n. 2, p. 184-191, 2008.-
dc.identifier.issn1806-8324-
dc.identifier.issn1807-3107-
dc.identifier.urihttp://hdl.handle.net/11449/70520-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/70520-
dc.description.abstractThis research evaluated the bone repair process in surgical defects created on the parietal bones of diabetic rabbits using the guided bone regeneration technique to observe the effects of alloxan in the induction of diabetes mellitus. Twenty-four adult rabbits were divided into three study groups: control (C), diabetic (D) and diabetic associated to polytetrafluoroethylene (PTFE) membrane (D-PTFE). For diabetes induction the animals received one dose of monohydrated alloxan (90 mg/kg) by intravenous administration in the auricular or femoral vein. In group D-PTFE the membrane covered both the floor and the surface of the bone defect. In groups D and C, the bone defect was filled up with blood clot. The specimens were fixed in 10% formol and prepared for histomorphometric analysis. The results showed that the 90 mg/kg dose of monohydrate alloxan was sufficient to promote diabetes mellitus when administered in the auricular vein. Bone regeneration was slower in the diabetic group when compared with the control and diabetic-PTFE groups, but there was no significant statistical difference between the two experimental groups (D and D-PTFE). The oral and general clinical complications among the diabetics were weight loss, polyuria, polyphagia and severe chronic gingivitis.en
dc.format.extent184-191-
dc.language.isoeng-
dc.sourceScopus-
dc.subjectAlloxan-
dc.subjectBone regeneration-
dc.subjectDiabetes complications-
dc.subjectDiabetes mellitus-
dc.subjectalloxan-
dc.subjectbiomaterial-
dc.subjectpolitef-
dc.subjectanalysis of variance-
dc.subjectanimal-
dc.subjectbone regeneration-
dc.subjectchemically induced disorder-
dc.subjectdisease model-
dc.subjectdrug effect-
dc.subjectexperimental diabetes mellitus-
dc.subjectpancreas-
dc.subjectpathophysiology-
dc.subjectphysiology-
dc.subjectrabbit-
dc.subjectrandomization-
dc.subjectskull-
dc.subjectwound healing-
dc.subjectAnalysis of Variance-
dc.subjectAnimals-
dc.subjectBiocompatible Materials-
dc.subjectBone Regeneration-
dc.subjectDiabetes Mellitus, Experimental-
dc.subjectDisease Models, Animal-
dc.subjectPancreas-
dc.subjectParietal Bone-
dc.subjectPolytetrafluoroethylene-
dc.subjectRabbits-
dc.subjectRandom Allocation-
dc.subjectSkull-
dc.subjectWound Healing-
dc.titleBone regeneration in cranioplasty and clinical complications in rabbits with alloxan-induced diabetesen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationOral Biopathology Program School of Dentistry of São Jose dos Campos São Paulo State University (UNESP), São Paulo-
dc.description.affiliationSpecial Health Care Needs Association (ASPE) Bioscience Center for Special Health Care Needs (CEBAPE/UNESP) São Paulo State University (UNESP), São Paulo, SP-
dc.description.affiliation, Av. Eng. Francisco José Lango, 777, São José dos Campos, SP 12245-000-
dc.description.affiliationUnespOral Biopathology Program School of Dentistry of São Jose dos Campos São Paulo State University (UNESP), São Paulo-
dc.description.affiliationUnespSpecial Health Care Needs Association (ASPE) Bioscience Center for Special Health Care Needs (CEBAPE/UNESP) São Paulo State University (UNESP), São Paulo, SP-
dc.identifier.doi10.1590/S1806-83242008000200015-
dc.identifier.scieloS1806-83242008000200015-
dc.rights.accessRightsAcesso aberto-
dc.identifier.file2-s2.0-48249138149.pdf-
dc.relation.ispartofBrazilian Oral Research-
dc.identifier.scopus2-s2.0-48249138149-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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