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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/72349
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dc.contributor.authorOliveira, Leandro Gustavo de-
dc.contributor.authorCâmara, Niels Olsen S.-
dc.contributor.authorPeraçoli, José Carlos-
dc.contributor.authorPeraçoli, Maria Terezinha Serrão-
dc.contributor.authorMoron, Antonio F.-
dc.contributor.authorSass, Nelson-
dc.date.accessioned2014-05-27T11:25:30Z-
dc.date.accessioned2016-10-25T18:33:44Z-
dc.date.available2014-05-27T11:25:30Z-
dc.date.available2016-10-25T18:33:44Z-
dc.date.issued2011-04-01-
dc.identifierhttp://dx.doi.org/10.1016/j.preghy.2011.02.002-
dc.identifier.citationPregnancy Hypertension, v. 1, n. 2, p. 129-131, 2011.-
dc.identifier.issn2210-7789-
dc.identifier.urihttp://hdl.handle.net/11449/72349-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/72349-
dc.description.abstractIntense inflammatory response and an anti-angiogenic state have been implicated in the pathogenesis of preeclampsia. Here, we investigated this hypothesis evaluating the serum concentrations of CXCL10/IP-10, sFlt-1, and PlGF in women with early-onset preeclampsia. CXCL10/IP-10 was measured by Cytometric Bead Array. sFlt-1 and PlGF were measured by automated electrochemiluminescence immunoassay. The median serum concentration of CXCL10/IP-10 was 109.5 pg/mL in preeclamptic women, as compared with 52.28 pg/mL in the controls (P = 0.0028). The mean serum level of sFlt-1 was 13,636 pg/mL in preeclamptic women, as compared with 2020 pg/mL in the controls (P < 0.0001). PlGF levels were significantly lower in women with preeclampsia. © 2011 International Society for the Study of Hypertension in Pregnancy. Published by Elsevier B.V. All rights reserved.en
dc.format.extent129-131-
dc.language.isoeng-
dc.sourceScopus-
dc.subjectAngiogenic factors-
dc.subjectInflammation-
dc.subjectIP-10-
dc.subjectPlGF-
dc.subjectPreeclampsia-
dc.subjectsFlt-1-
dc.subjectgamma interferon inducible protein 10-
dc.subjectplacental growth factor-
dc.subjectvasculotropin receptor 1-
dc.subjectadult-
dc.subjectchemoluminescence-
dc.subjectclinical article-
dc.subjectcontrolled study-
dc.subjectcytometry-
dc.subjectfemale-
dc.subjecthuman-
dc.subjecthypothesis-
dc.subjectimmunoassay-
dc.subjectinflammation-
dc.subjectpathogenesis-
dc.subjectpreeclampsia-
dc.subjectprotein blood level-
dc.titleSFlt-1 and IP-10 in women with early-onset preeclampsiaen
dc.typeoutro-
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)-
dc.contributor.institutionUniversidade de São Paulo (USP)-
dc.contributor.institutionHospital e Maternidade Vila Nova Cachoeirinha-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationObstetrics Department Universidade Federal de São Paulo, Rua Napoleão de Barros, 875, Vila Clementino, São Paulo 04024-002-
dc.description.affiliationLaboratory of Immunobiology of Transplantation Universidade de São Paulo-
dc.description.affiliationLaboratory of Clinical and Experimental Investigation Hospital e Maternidade Vila Nova Cachoeirinha, São Paulo-
dc.description.affiliationObstetrics Department Universidade Estadual de São Paulo, Botucatu-
dc.description.affiliationUnespObstetrics Department Universidade Estadual de São Paulo, Botucatu-
dc.identifier.doi10.1016/j.preghy.2011.02.002-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofPregnancy Hypertension-
dc.identifier.scopus2-s2.0-79952655899-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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