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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/72656
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dc.contributor.authorCamargo, Carlos Henrique-
dc.contributor.authorBruder-Nascimento, Ariane-
dc.contributor.authorMondelli, Alessandro Lia-
dc.contributor.authorMontelli, Augusto Cezar-
dc.contributor.authorSadatsune, Terue-
dc.date.accessioned2014-05-27T11:25:59Z-
dc.date.accessioned2016-10-25T18:34:26Z-
dc.date.available2014-05-27T11:25:59Z-
dc.date.available2016-10-25T18:34:26Z-
dc.date.issued2011-09-01-
dc.identifierhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000500011-
dc.identifier.citationBrazilian Journal of Infectious Diseases, v. 15, n. 5, p. 478-481, 2011.-
dc.identifier.issn1413-8670-
dc.identifier.issn1678-4391-
dc.identifier.urihttp://hdl.handle.net/11449/72656-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/72656-
dc.description.abstractPhenotypic and genotypic SPM and IMP metallo-β-lactamases (MBL) detection and also the determination of minimal inhibitory concentrations (MIC) to imipenem, meropenem and ceftazidime were evaluated in 47 multidrug-resistant Pseudomonas aeruginosa isolates from clinical specimens. Polymerase chain reaction detected 14 positive samples to either blaSPM or blaIMP genes, while the best phenotypic assay (ceftazidime substrate and mercaptopropionic acid inhibitor) detected 13 of these samples. Imipenem, meropenem and ceftazidime MICs were higher for MBL positive compared to MBL negative isolates. We describe here the SPM and IMP MBL findings in clinical specimens of P. aeruginosa from the University Hospital of Botucatu Medical School, São Paulo, Brazil, that reinforce local studies showing the high spreading of blaSPM and blaIMP genes among Brazilian clinical isolates. © 2011 Elsevier Editora Ltda.en
dc.format.extent478-481-
dc.language.isoeng-
dc.sourceScopus-
dc.subjectCarbapenems-
dc.subjectDrug resistance, bacterial-
dc.subjectMetalloproteins-
dc.subjectPolymerase chain reaction-
dc.subjectPseudomonas aeruginosa-
dc.subjectceftazidime-
dc.subjectimipenem-
dc.subjectimipenemase metallo beta lactamase-
dc.subjectmercaptopropionic acid-
dc.subjectmeropenem-
dc.subjectmetallo beta lactamase-
dc.subjectpolymyxin B-
dc.subjectpropionic acid derivative-
dc.subjectSao Paulo metallo beta lactamase-
dc.subjectunclassified drug-
dc.subjectantibiotic sensitivity-
dc.subjectbacterial gene-
dc.subjectbacterial transmission-
dc.subjectbacterium isolate-
dc.subjectbla IMP gene-
dc.subjectbla SPM gene-
dc.subjectblood culture-
dc.subjectbody fluid-
dc.subjectBrazil-
dc.subjectcontrolled study-
dc.subjectenzyme analysis-
dc.subjectgenotype-
dc.subjectminimum inhibitory concentration-
dc.subjectmultidrug resistance-
dc.subjectnonhuman-
dc.subjectphenotype-
dc.subjectpolymerase chain reaction-
dc.subjectsensitivity and specificity-
dc.subjecttertiary health care-
dc.subjecttest strip-
dc.subjectuniversity hospital-
dc.subjecturine culture-
dc.subjectAnti-Bacterial Agents-
dc.subjectbeta-Lactamases-
dc.subjectCeftazidime-
dc.subjectCross Infection-
dc.subjectGenes, Bacterial-
dc.subjectGenotype-
dc.subjectHospitals, Public-
dc.subjectHumans-
dc.subjectImipenem-
dc.subjectMicrobial Sensitivity Tests-
dc.subjectPhenotype-
dc.subjectPolymerase Chain Reaction-
dc.subjectThienamycins-
dc.titleDetection of SPM and IMP metallo-β-lactamases in clinical specimens of Pseudomonas aeruginosa from a Brazilian public tertiary hospitalen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationBiologist; MSc Student Universidade Estatual Paulista (UNESP), Botucatu, SP-
dc.description.affiliationUNESP, Botucatu, SP-
dc.description.affiliationUnespBiologist; MSc Student Universidade Estatual Paulista (UNESP), Botucatu, SP-
dc.description.affiliationUnespUNESP, Botucatu, SP-
dc.identifier.scieloS1413-86702011000500011-
dc.rights.accessRightsAcesso aberto-
dc.identifier.file2-s2.0-82855182014.pdf-
dc.relation.ispartofBrazilian Journal of Infectious Diseases-
dc.identifier.scopus2-s2.0-82855182014-
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