Você está no menu de acessibilidade

Utilize este identificador para citar ou criar um link para este item: http://acervodigital.unesp.br/handle/11449/7308
Título: 
The role of obesity as a modifying factor in patients undergoing non-surgical periodontal therapy
Autor(es): 
Instituição: 
  • Educ Fdn Barretos UNIFEB
  • Universidade Estadual Paulista (UNESP)
ISSN: 
0022-3492
Financiador: 
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Número do financiamento: 
CNPq: 476390/2007-9
Resumo: 
Background: Earlier studies have shown an association between obesity and periodontitis, which is mediated by cytokine production. The aim of this study is to assess the role of obesity as a modifying factor on periodontal clinical parameters and on circulating proinflammatory cytokine levels in subjects undergoing non-surgical periodontal treatment.Methods: Twenty-seven obese subjects and 25 normal-weight subjects were enrolled in this study. Subjects in both groups had generalized chronic periodontitis. The periodontal parameters measured before and 3 months after non-surgical periodontal therapy were: visible plaque index, bleeding gingival index, bleeding on probing, probing depth, and clinical attachment level. In addition, subjects underwent anthropometric measurements and serum analyses of fasting glucose, glycated hemoglobin, interleukin-1 beta, interleukin-6, tumor necrosis factor-alpha, and interferon-gamma.Results: Periodontal therapy significantly decreased visible plaque index, bleeding gingival index, bleeding on probing, probing depth of 4 to 6 mm, probing depth >= 7 mm, clinical attachment level of 4 to 6 mm, and clinical attachment level >= 7 mm in both groups (P <= 0.05). Circulating proinflammatory cytokines significantly decreased in obese and normal-weight subjects after periodontal treatment (P <= 0.05). However, interleukin-6 and tumor necrosis factor-a levels remained higher in obese subjects 3 months after treatment (P <= 0.05).Conclusion: Obesity does not seem to play a negative role by interfering in the improvement of the periodontal clinical response or decreasing circulating proinflammatory cytokine levels after periodontal treatment. J Periodontol 2011;82:676-682.
Data de publicação: 
1-Mai-2011
Citação: 
Journal of Periodontology. Chicago: Amer Acad Periodontology, v. 82, n. 5, p. 676-682, 2011.
Duração: 
676-682
Publicador: 
Amer Acad Periodontology
Palavras-chaves: 
  • Chronic periodontitis
  • clinical trial
  • cytokines
  • dental scaling
  • obesity
  • root planing
Fonte: 
http://dx.doi.org/10.1902/jop.2010.100545
Endereço permanente: 
Direitos de acesso: 
Acesso restrito
Tipo: 
outro
Fonte completa:
http://repositorio.unesp.br/handle/11449/7308
Aparece nas coleções:Artigos, TCCs, Teses e Dissertações da Unesp

Não há nenhum arquivo associado com este item.
 

Itens do Acervo digital da UNESP são protegidos por direitos autorais reservados a menos que seja expresso o contrário.