You are in the accessibility menu

Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorZuza, Elizangela P.-
dc.contributor.authorBarroso, Eliane M.-
dc.contributor.authorCarrareto, Ana Luiza V.-
dc.contributor.authorPires, Juliana R.-
dc.contributor.authorCarlos, Iracilda Zeppone-
dc.contributor.authorTheodoro, Letícia Helena-
dc.contributor.authorToledo, Benedicto Egbert C.-
dc.identifier.citationJournal of Periodontology. Chicago: Amer Acad Periodontology, v. 82, n. 5, p. 676-682, 2011.-
dc.description.abstractBackground: Earlier studies have shown an association between obesity and periodontitis, which is mediated by cytokine production. The aim of this study is to assess the role of obesity as a modifying factor on periodontal clinical parameters and on circulating proinflammatory cytokine levels in subjects undergoing non-surgical periodontal treatment.Methods: Twenty-seven obese subjects and 25 normal-weight subjects were enrolled in this study. Subjects in both groups had generalized chronic periodontitis. The periodontal parameters measured before and 3 months after non-surgical periodontal therapy were: visible plaque index, bleeding gingival index, bleeding on probing, probing depth, and clinical attachment level. In addition, subjects underwent anthropometric measurements and serum analyses of fasting glucose, glycated hemoglobin, interleukin-1 beta, interleukin-6, tumor necrosis factor-alpha, and interferon-gamma.Results: Periodontal therapy significantly decreased visible plaque index, bleeding gingival index, bleeding on probing, probing depth of 4 to 6 mm, probing depth >= 7 mm, clinical attachment level of 4 to 6 mm, and clinical attachment level >= 7 mm in both groups (P <= 0.05). Circulating proinflammatory cytokines significantly decreased in obese and normal-weight subjects after periodontal treatment (P <= 0.05). However, interleukin-6 and tumor necrosis factor-a levels remained higher in obese subjects 3 months after treatment (P <= 0.05).Conclusion: Obesity does not seem to play a negative role by interfering in the improvement of the periodontal clinical response or decreasing circulating proinflammatory cytokine levels after periodontal treatment. J Periodontol 2011;82:676-682.en
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.publisherAmer Acad Periodontology-
dc.sourceWeb of Science-
dc.subjectChronic periodontitisen
dc.subjectclinical trialen
dc.subjectdental scalingen
dc.subjectroot planingen
dc.titleThe role of obesity as a modifying factor in patients undergoing non-surgical periodontal therapyen
dc.contributor.institutionEduc Fdn Barretos UNIFEB-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationEduc Fdn Barretos UNIFEB, Sch Dent, Dept Master Dent Sci Course, Barretos, Brazil-
dc.description.affiliationSão Paulo State Univ UNESP, Sch Pharm, Dept Clin Anal, Araraquara, Brazil-
dc.description.affiliationUnespSão Paulo State Univ UNESP, Sch Pharm, Dept Clin Anal, Araraquara, Brazil-
dc.description.sponsorshipIdCNPq: 476390/2007-9-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofJournal of Periodontology-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.