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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/73510
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dc.contributor.authorVieira, Daniela C.M.-
dc.contributor.authorRicarte, Patrícia C.-
dc.contributor.authorSalgado, Hérida R.N.-
dc.date.accessioned2014-05-27T11:26:56Z-
dc.date.accessioned2016-10-25T18:37:53Z-
dc.date.available2014-05-27T11:26:56Z-
dc.date.available2016-10-25T18:37:53Z-
dc.date.issued2012-08-22-
dc.identifierhttp://www.latamjpharm.org/resumenes/31/5/LAJOP_31_5_2_2.pdf-
dc.identifier.citationLatin American Journal of Pharmacy, v. 31, n. 5, p. 746-750, 2012.-
dc.identifier.issn0326-2383-
dc.identifier.urihttp://hdl.handle.net/11449/73510-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/73510-
dc.description.abstractThe validation of a microbiological assay, applying agar diffusion method for determination of the active of cefuroxime in power for injection, is described. Using a strain of Micrococcus luteus ATCC 9341 as the test organism, cefuroxime was measured in concentrations ranging from 30.0 to 120.0 μg/mL. The method validation showed that it is linear (r = 0.9999), precise (relative standard deviation = 0.37%) and accurate (it measured the added quantities). Microbiological assay is satisfactory for quantitation of cefuroxime in powder for injection and the validity of the proposed bioassay, which is a simple and a useful alternative methodology for cefuroxime determination in routine quality control.en
dc.format.extent746-750-
dc.language.isoeng-
dc.sourceScopus-
dc.subjectCefuroxime-
dc.subjectCephalosporins-
dc.subjectMicrobiological assay-
dc.subjectQuality control-
dc.subjectValidation-
dc.subjectcefuroxime-
dc.subjectagar diffusion-
dc.subjectbacterial growth-
dc.subjectbacterial strain-
dc.subjectbacterium culture-
dc.subjectcalibration-
dc.subjectcorrelation coefficient-
dc.subjectdrug determination-
dc.subjectdrug purity-
dc.subjectdrug structure-
dc.subjectlimit of detection-
dc.subjectlimit of quantitation-
dc.subjectmicrobiology-
dc.subjectMicrococcus luteus-
dc.subjectquality control-
dc.subjectvalidation study-
dc.titleValidation of microbiological assay for determination of cefuroxime in injectable preparationsen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationCiências Farmacêuticas de Araraquara Unesp, Rodovia Araraquara-Jaú, km 1, CEP: 14801-902 Araraquara-SP-
dc.description.affiliationUnespCiências Farmacêuticas de Araraquara Unesp, Rodovia Araraquara-Jaú, km 1, CEP: 14801-902 Araraquara-SP-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofLatin American Journal of Pharmacy-
dc.identifier.scopus2-s2.0-84865083152-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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