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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/74197
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dc.contributor.authorRavalli, A.-
dc.contributor.authorPilon Dos Santos, G.-
dc.contributor.authorFerroni, M.-
dc.contributor.authorFaglia, G.-
dc.contributor.authorYamanaka, Hideko-
dc.contributor.authorMarrazza, G.-
dc.date.accessioned2014-05-27T11:27:29Z-
dc.date.accessioned2016-10-25T18:41:00Z-
dc.date.available2014-05-27T11:27:29Z-
dc.date.available2016-10-25T18:41:00Z-
dc.date.issued2013-01-01-
dc.identifierhttp://dx.doi.org/10.1016/j.snb.2012.10.017-
dc.identifier.citationSensors and Actuators, B: Chemical, v. 179, p. 194-200.-
dc.identifier.issn0925-4005-
dc.identifier.urihttp://hdl.handle.net/11449/74197-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/74197-
dc.description.abstractThis paper describes the optimisation and the analytical performances of a label-free impedimetric immunosensor for the detection of tumour marker CA125 based on gold nanoparticles modified screen-printed graphite electrode. Experimental conditions of each step for the developed immunosensor were studied and optimised. The immunosensor response varied linearly (r2 = 0.996) with antigen concentration between 0 and 100 U/mL. The estimated detection limit was 6.7 U/mL. The electrochemical immunosensor allowed unambiguous identification of CA125, while no significant non-specific signal was detected in the case of all negative controls. The analytical usefulness of the impedimetric immunosensor was finally demonstrated analysing serum samples. © 2012 Elsevier B.V. All rights reserved.en
dc.format.extent194-200-
dc.language.isoeng-
dc.sourceScopus-
dc.subjectCA125-
dc.subjectGold nanoparticles-
dc.subjectImpedimetric immunosensor-
dc.subjectScreen-printed electrode-
dc.subjectTumour marker-
dc.subjectAnalytical performance-
dc.subjectDetection limits-
dc.subjectElectrochemical immunosensors-
dc.subjectExperimental conditions-
dc.subjectGold Nanoparticles-
dc.subjectImpedimetric immunosensors-
dc.subjectScreen printed electrodes-
dc.subjectGold-
dc.subjectGraphite electrodes-
dc.subjectMetal nanoparticles-
dc.subjectTumors-
dc.subjectImmunosensors-
dc.titleNew label free CA125 detection based on gold nanostructured screen-printed electrodeen
dc.typeoutro-
dc.contributor.institutionUniversity of Florence-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionCNR-IDASC-
dc.description.affiliationDepartment of Chemistry Ugo Schiff University of Florence, Via della Lastruccia 3, 50019 Sesto Fiorentino, Florence-
dc.description.affiliationDepartment of Analytical Chemistry São Paulo State University (UNESP), Rua Prof. Francisco Degni, 14800-900 Araraquara, SP-
dc.description.affiliationSENSOR Laboratory - Department of Physics and Chemistry University of Brescia CNR-IDASC, Via Valotti 9, 25133 Brescia-
dc.description.affiliationUnespDepartment of Analytical Chemistry São Paulo State University (UNESP), Rua Prof. Francisco Degni, 14800-900 Araraquara, SP-
dc.identifier.doi10.1016/j.snb.2012.10.017-
dc.identifier.wosWOS:000316588100024-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofSensors and Actuators B: Chemical-
dc.identifier.scopus2-s2.0-84880921300-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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