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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/74522
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dc.contributor.authorPereira Braga, Camila-
dc.contributor.authorMomentti, Ana Carolina-
dc.contributor.authorBarbosa Peixoto, Fernando-
dc.contributor.authorde Fátima Ferreira Baptista, Rafaela-
dc.contributor.authordos Santos, Felipe André-
dc.contributor.authorFava, Fábio Henrique-
dc.contributor.authorFernandes, Ana Angélica Henrique-
dc.date.accessioned2014-05-27T11:28:20Z-
dc.date.accessioned2016-10-25T18:43:27Z-
dc.date.available2014-05-27T11:28:20Z-
dc.date.available2016-10-25T18:43:27Z-
dc.date.issued2013-02-01-
dc.identifierhttp://dx.doi.org/10.1139/cjpp-2012-0173-
dc.identifier.citationCanadian Journal of Physiology and Pharmacology, v. 91, n. 2, p. 171-177, 2013.-
dc.identifier.issn0008-4212-
dc.identifier.issn1205-7541-
dc.identifier.urihttp://hdl.handle.net/11449/74522-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/74522-
dc.description.abstractAmong the numerous coadjuvant therapies that could influence the incidence and progression of diabetic complications, antioxidants and flavonoids are currently being tested in clinical trials. We investigated the effect of quercetin on biochemical parameters in streptozotocin-induced (60 mg/kg body mass, by intraperitoneal injection) diabetic rats. A total of 32 female Wistar rats were distributed among 4 groups as follows: control (G1); control treated with quercetin (G2); diabetic (G3); and diabetic treated with quercetin (G4). Quercetin administered to pregnant diabetic rats controlled dyslipidemia and improved lipid profiles in diabetes mellitus, regulated oxidative stress by reducing the generation of lipid hydroperoxides, and increased the activity of the antioxidant enzyme glutathione peroxidase.en
dc.format.extent171-177-
dc.language.isoeng-
dc.sourceScopus-
dc.subjectDiabetes mellitus-
dc.subjectLipid profile-
dc.subjectOxidative stress-
dc.subjectPregnancy-
dc.subjectQuercetin-
dc.subjectantidiabetic agent-
dc.subjectglutathione peroxidase-
dc.subjectlipid hydroperoxide-
dc.subjectquercetin-
dc.subjectstreptozocin-
dc.subjectanimal experiment-
dc.subjectantidiabetic activity-
dc.subjectbiochemistry-
dc.subjectcontrolled study-
dc.subjectdrug effect-
dc.subjectdyslipidemia-
dc.subjectenzyme activity-
dc.subjectfemale-
dc.subjectfood intake-
dc.subjectnonhuman-
dc.subjectoxidative stress-
dc.subjectpregnancy diabetes mellitus-
dc.subjectpriority journal-
dc.subjectrat-
dc.subjectAnimals-
dc.subjectAntioxidants-
dc.subjectBlood Glucose-
dc.subjectDiabetes Mellitus, Experimental-
dc.subjectDiabetes Mellitus, Type 1-
dc.subjectFemale-
dc.subjectGlutathione Peroxidase-
dc.subjectLipid Peroxides-
dc.subjectLipids-
dc.subjectMale-
dc.subjectOxidative Stress-
dc.subjectPregnancy in Diabetics-
dc.subjectRats-
dc.subjectRats, Wistar-
dc.subjectTreatment Outcome-
dc.titleInfluence of treatment with quercetin on lipid parameters and oxidative stress of pregnant diabetic ratsen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationDepartamento de Química e Bioquímica Instituto de Biociências, Campus de Botucatu Universidade Estadual Paulista Júlio de Mesquita Filho, UNESP, 18618-970, Botucatu, SP-
dc.description.affiliationDepartamento de Farmacologia Instituto de Biociências, Campus de Botucatu Universidade Estadual Paulista 'Júlio de Mesquita Filho', UNESP, 18618-970, Botucatu, SP-
dc.description.affiliationUnespDepartamento de Química e Bioquímica Instituto de Biociências, Campus de Botucatu Universidade Estadual Paulista Júlio de Mesquita Filho, UNESP, 18618-970, Botucatu, SP-
dc.description.affiliationUnespDepartamento de Farmacologia Instituto de Biociências, Campus de Botucatu Universidade Estadual Paulista 'Júlio de Mesquita Filho', UNESP, 18618-970, Botucatu, SP-
dc.identifier.doi10.1139/cjpp-2012-0173-
dc.identifier.wosWOS:000315789900011-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofCanadian Journal of Physiology and Pharmacology-
dc.identifier.scopus2-s2.0-84874636972-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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