You are in the accessibility menu

Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/7500
Full metadata record
DC FieldValueLanguage
dc.contributor.authorCalvo, Tamara Regina-
dc.contributor.authorPrimila Cardoso, Cassia Regina-
dc.contributor.authorda Silva Moura, Adriana Candido-
dc.contributor.authorSantos, Lourdes Campaner dos-
dc.contributor.authorSyllos Colus, Ilce Mara-
dc.contributor.authorVilegas, Wagner-
dc.contributor.authorVaranda, Eliana Aparecida-
dc.date.accessioned2014-05-20T13:24:18Z-
dc.date.available2014-05-20T13:24:18Z-
dc.date.issued2011-01-01-
dc.identifierhttp://dx.doi.org/10.1093/ecam/nep123-
dc.identifier.citationEvidence-based Complementary and Alternative Medicine. New York: Hindawi Publishing Corporation, p. 9, 2011.-
dc.identifier.issn1741-427X-
dc.identifier.urihttp://hdl.handle.net/11449/7500-
dc.description.abstractIndigofera truxillensis and I. suffruticosa, are used as a source of indigo dye and to treat several diseases. The mutagenic activity of the methanolic extracts from aerial parts, glycerolipid, flavonoid and alkaloid fractions of the extract were evaluated by means of Salmonella/microsome assays using TA100, TA98, TA102 and TA97a strains. The methanolic extract of I. truxillensis showed mutagenic activity in the TA98 strain without S9 while glycerolipid fraction was devoid of activity. The flavonoid and alkaloid fractions of both plants showed mutagenicity. Chemical analysis of flavonoid fractions of I. truxillensis and I. suffruticosa resulted in the identification of kaempferol, quercetin and their derivatives. The alkaloid fraction of both the species contained indigo and indirubin and indigo was found mainly responsible for the mutagenic activity.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.format.extent9-
dc.language.isoeng-
dc.publisherHindawi Publishing Corporation-
dc.sourceWeb of Science-
dc.titleMutagenic Activity of Indigofera truxillensis and I. suffruticosa Aerial Partsen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionUniversidade Estadual de Londrina (UEL)-
dc.description.affiliationUNESP São Paulo State Univ, Fac Ciencias Farmaceut, Dept Ciencias Biol, BR-14801902 Araraquara, SP, Brazil-
dc.description.affiliationUNESP São Paulo State Univ, Inst Quim Araraquara, Dept Quim Organ, BR-14800900 São Paulo, Brazil-
dc.description.affiliationUEL Londrina State Univ, Ctr Biol Sci, Dept Gen Biol, BR-86051990 Londrina, PR, Brazil-
dc.description.affiliationUnespUNESP São Paulo State Univ, Fac Ciencias Farmaceut, Dept Ciencias Biol, BR-14801902 Araraquara, SP, Brazil-
dc.description.affiliationUnespUNESP São Paulo State Univ, Inst Quim Araraquara, Dept Quim Organ, BR-14800900 São Paulo, Brazil-
dc.identifier.doi10.1093/ecam/nep123-
dc.identifier.wosWOS:000293413300001-
dc.rights.accessRightsAcesso aberto-
dc.identifier.fileWOS000293413300001.pdf-
dc.relation.ispartofEvidence-based Complementary and Alternative Medicine-
dc.identifier.orcid0000-0003-3032-2556pt
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

There are no files associated with this item.
Show simple item record Show full item record   View Statistics
 

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.