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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/75214
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dc.contributor.authorClaudiano, Gustavo da Silva-
dc.contributor.authorPetrillo, Thalita R.-
dc.contributor.authorManrique, Wilson G.-
dc.contributor.authorCastro, Marcello P.-
dc.contributor.authorLoureiro, Bruna A.-
dc.contributor.authorMarcusso, Paulo F.-
dc.contributor.authorBelo, Marco A.A.-
dc.contributor.authorMoraes, Julieta R.E.-
dc.contributor.authorDe Moraes, Flávio Ruas-
dc.date.accessioned2014-05-27T11:29:01Z-
dc.date.accessioned2016-10-25T18:47:54Z-
dc.date.available2014-05-27T11:29:01Z-
dc.date.available2016-10-25T18:47:54Z-
dc.date.issued2013-05-01-
dc.identifierhttp://dx.doi.org/10.1016/j.fsi.2013.01.006-
dc.identifier.citationFish and Shellfish Immunology, v. 34, n. 5, p. 1057-1062, 2013.-
dc.identifier.issn1050-4648-
dc.identifier.issn1095-9947-
dc.identifier.urihttp://hdl.handle.net/11449/75214-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/75214-
dc.description.abstractA total of 360 pacus (Piaractus mesopotamicus) were used to study vascular permeability (VP) and inflammatory cell component (CC) in induced aerocystitis in P. mesopotamicus through inoculation of inactivated Aeromonas hydrophila, and the effect of steroidal and nonsteroidal anti-inflammatory drugs. It was observed that after inoculation of A. hydrophila, the maximum VP occurred 180 min post-stimulus (MPS). Pretreatment with anti-inflammatory drugs inhibited VP, and the inhibitory effect of dexamethasone was seen earlier than the effects caused by meloxicam and indomethacin. Inoculation of the bacterium caused a gradual increase in the accumulation of cells, which reached a maximum 24 h post-stimulus (HPS). Pretreatment with dexamethasone, indomethacin and meloxicam reduced the accumulation of lymphocytes, thrombocytes, granulocytes and macrophages. There was no significant difference between the different doses of the drugs tested. The results suggest that eicosanoids and pro-inflammatory cytokines participate in chemical mediation in acute inflammation in pacus. © 2013 Elsevier Ltd.en
dc.format.extent1057-1062-
dc.language.isoeng-
dc.sourceScopus-
dc.subjectChemical mediators-
dc.subjectEvans blue-
dc.subjectInflammation-
dc.subjectTeleost-
dc.subjectVascular alteration-
dc.subjectantiinflammatory agent-
dc.subjectbacterial vaccine-
dc.subjectcytokine-
dc.subjectdexamethasone-
dc.subjecticosanoid-
dc.subjectinactivated vaccine-
dc.subjectindometacin-
dc.subjectmeloxicam-
dc.subjectthiazine derivative-
dc.subjectthiazole derivative-
dc.subjectAeromonas hydrophila-
dc.subjectanimal-
dc.subjectanimal disease-
dc.subjectcapillary permeability-
dc.subjectcell structure-
dc.subjectCharacidae-
dc.subjectdose response-
dc.subjectGram negative infection-
dc.subjectimmunology-
dc.subjectmetabolism-
dc.subjectmicrobiology-
dc.subjecttime-
dc.subjectAnimals-
dc.subjectAnti-Inflammatory Agents-
dc.subjectBacterial Vaccines-
dc.subjectCapillary Permeability-
dc.subjectCellular Structures-
dc.subjectCytokines-
dc.subjectDexamethasone-
dc.subjectDose-Response Relationship, Drug-
dc.subjectEicosanoids-
dc.subjectGram-Negative Bacterial Infections-
dc.subjectIndomethacin-
dc.subjectThiazines-
dc.subjectThiazoles-
dc.subjectTime Factors-
dc.subjectVaccines, Inactivated-
dc.subjectBacteria (microorganisms)-
dc.subjectPiaractus mesopotamicus-
dc.subjectTeleostei-
dc.titleAcute aerocystitis in Piaractus mesopotamicus: Participation of eicosanoids and pro-inflammatory cytokinesen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationDepartment of Veterinary Pathology School of Agrarian and Veterinary Sciences São Paulo State University (UNESP), Via Prof. Paulo Donato Castellane, km 05, Jaboticabal, SP 14884-900-
dc.description.affiliationUnespDepartment of Veterinary Pathology School of Agrarian and Veterinary Sciences São Paulo State University (UNESP), Via Prof. Paulo Donato Castellane, km 05, Jaboticabal, SP 14884-900-
dc.identifier.doi10.1016/j.fsi.2013.01.006-
dc.identifier.wosWOS:000317870600005-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofFish and Shellfish Immunology-
dc.identifier.scopus2-s2.0-84875809339-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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