You are in the accessibility menu

Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorBruschi, M. L.-
dc.contributor.authorCardoso, MLC-
dc.contributor.authorLucchesi, M. B.-
dc.contributor.authorGremiao, MPD-
dc.identifier.citationInternational Journal of Pharmaceutics. Amsterdam: Elsevier B.V., v. 264, n. 1-2, p. 45-55, 2003.-
dc.description.abstractGelatin microparticles containing propolis extractive solution (PES) were prepared by spray-drying technique. The optimization of the spray-drying operating conditions and the proportions of gelatin and mannitol were investigated. Regular particle morphology was obtained when mannitol was used, whereas mannitol absence produced a substantial number of coalesced and agglomerated microparticles. Microparticles had a mean diameter of 2.70 mum without mannitol and 2.50 mum with mannitol. The entrapment efficiency for propolis of the microparticles was upto 41 % without mannitol and 39% with mannitol. The microencapsulation by spray-drying technique maintained the activity of propolis against Staphylococcus aureus. These gelatin microparticles containing propolis would be useful for developing intermediary or eventual propolis dosage form without the PES' strong and unpleasant taste, aromatic odour, and presence of ethanol. (C) 2003 Elsevier B.V. All rights reserved.en
dc.publisherElsevier B.V.-
dc.sourceWeb of Science-
dc.subjectmicroparticle characterizationpt
dc.titleGelatin microparticles containing propolis obtained by spray-drying technique: preparation and characterizationen
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionUniversidade Estadual de Maringá (UEM)-
dc.description.affiliationUNESP, Programa Pos Grad Ciências Farmaceut, BR-14802902 Araraquara, SP, Brazil-
dc.description.affiliationUniv Estadual Maringa, Dept Farmacia & Farmacol, BR-87020900 Maringa, Parana, Brazil-
dc.description.affiliationUnespUNESP, Programa Pos Grad Ciências Farmaceut, BR-14802902 Araraquara, SP, Brazil-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofInternational Journal of Pharmaceutics-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.