Please use this identifier to cite or link to this item:
http://acervodigital.unesp.br/handle/11449/75774
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kichuk, Stephen A. | - |
dc.contributor.author | Torres, Albina Rodrigues | - |
dc.contributor.author | Fontenelle, Leonardo F. | - |
dc.contributor.author | Rosário, Maria Conceição | - |
dc.contributor.author | Shavitt, Roseli G. | - |
dc.contributor.author | Miguel, Eurípedes C. | - |
dc.contributor.author | Pittenger, Christopher | - |
dc.contributor.author | Bloch, Michael H. | - |
dc.date.accessioned | 2014-05-27T11:29:49Z | - |
dc.date.accessioned | 2016-10-25T18:50:20Z | - |
dc.date.available | 2014-05-27T11:29:49Z | - |
dc.date.available | 2016-10-25T18:50:20Z | - |
dc.date.issued | 2013-07-01 | - |
dc.identifier | http://dx.doi.org/10.1016/j.pnpbp.2013.02.003 | - |
dc.identifier.citation | Progress in Neuro-Psychopharmacology and Biological Psychiatry, v. 44, p. 233-239. | - |
dc.identifier.issn | 0278-5846 | - |
dc.identifier.issn | 1878-4216 | - |
dc.identifier.uri | http://hdl.handle.net/11449/75774 | - |
dc.identifier.uri | http://acervodigital.unesp.br/handle/11449/75774 | - |
dc.description.abstract | Meta-analysis of the heterogeneous symptoms of obsessive-compulsive disorder (OCD) has found a four-factor structure of symptom dimensions consisting of cleaning, forbidden thoughts, symmetry, and hoarding. Research into age of onset of symptom dimensions has yielded inconsistent results, and it is unknown whether symptoms along these dimensions differ in their clinical course. We assessed age of onset and clinical course of different OCD symptom dimensions in a large cohort of adult patients. Nine-hundred fifty-five subjects were assessed using the Dimensional Yale-Brown Obsessive-Compulsive Scale. For age of onset analysis, we tested across three methods of classification: (1) primary (more severe) symptom dimension (2) clinically significant symptoms within a dimension or (3) any symptoms within a dimension. Age of onset was defined as the earliest age of onset reported for any individual item within a symptom dimension. For analysis of different types of clinical course, we used chi-square tests to assess for differences between primary symptom dimensions. OCD symptoms in the symmetry dimension had an earlier age of onset than other OCD symptom dimensions. These findings remained significant across all three methods of classification and controlling for gender and comorbid tics. No significant differences were found between the other dimensions. Subjects with primary OCD symptoms in the forbidden thoughts dimension were more likely to report a waxing-and-waning course, whereas symmetry symptoms were less likely to be associated with a waxing-and-waning course. © 2013. | en |
dc.format.extent | 233-239 | - |
dc.language.iso | eng | - |
dc.source | Scopus | - |
dc.subject | adult | - |
dc.subject | clinical feature | - |
dc.subject | comorbidity | - |
dc.subject | disease association | - |
dc.subject | disease classification | - |
dc.subject | disease severity | - |
dc.subject | female | - |
dc.subject | general condition deterioration | - |
dc.subject | human | - |
dc.subject | major clinical study | - |
dc.subject | male | - |
dc.subject | obsessive compulsive disorder | - |
dc.subject | obsessive hoarding | - |
dc.subject | onset age | - |
dc.subject | psychologic assessment | - |
dc.subject | sex difference | - |
dc.subject | symptom assessment | - |
dc.subject | symptomatology | - |
dc.subject | thought disorder | - |
dc.subject | tic | - |
dc.subject | Yale Brown Obsessive Compulsive Scale | - |
dc.title | Symptom dimensions are associated with age of onset and clinical course of obsessive-compulsive disorder | en |
dc.type | outro | - |
dc.contributor.institution | Yale University | - |
dc.contributor.institution | Universidade Estadual Paulista (UNESP) | - |
dc.contributor.institution | Federal University of Rio de Janeiro | - |
dc.contributor.institution | Universidade de São Paulo (USP) | - |
dc.description.affiliation | Department of Psychiatry Yale University | - |
dc.description.affiliation | Department of Neurology, Psychology and Psychiatry Botucatu Medical School Univ Estadual Paulista, Botucatu (SP) | - |
dc.description.affiliation | Anxiety and Depression Research Program Institute of Psychiatry Federal University of Rio de Janeiro, Rio de Janeiro (RJ) | - |
dc.description.affiliation | Department of Psychiatry Federal University of São Paulo Medical School, São Paulo (SP) | - |
dc.description.affiliation | Department of Psychiatry University of São Paulo Medical School, São Paulo (SP) | - |
dc.description.affiliation | Department of Psychology Yale University | - |
dc.description.affiliation | Child Study Center Yale University | - |
dc.description.affiliationUnesp | Department of Neurology, Psychology and Psychiatry Botucatu Medical School Univ Estadual Paulista, Botucatu (SP) | - |
dc.identifier.doi | 10.1016/j.pnpbp.2013.02.003 | - |
dc.identifier.wos | WOS:000320297400031 | - |
dc.rights.accessRights | Acesso restrito | - |
dc.relation.ispartof | Progress in Neuro-Psychopharmacology and Biological Psychiatry | - |
dc.identifier.scopus | 2-s2.0-84876323992 | - |
Appears in Collections: | Artigos, TCCs, Teses e Dissertações da Unesp |
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.