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dc.contributor.authorMiyague, Andre H.-
dc.contributor.authorMartins, Wellington P.-
dc.contributor.authorMachado, Jaqueline S. R.-
dc.contributor.authorPalei, Ana C.-
dc.contributor.authorAmaral, Lorena M.-
dc.contributor.authorTeixeira, Danielle M.-
dc.contributor.authorSandrim, Valeria C.-
dc.contributor.authorSertorio, Jonas T. C.-
dc.contributor.authorTanus-Santos, Jose E.-
dc.contributor.authorDuarte, Geraldo-
dc.contributor.authorCavalli, Ricardo C.-
dc.identifier.citationHypertension in Pregnancy, v. 32, n. 3, p. 225-234, 2013.-
dc.description.abstractObjectives. To compare maternal flow-mediated dilation (FMD) of the brachial artery and nitrite concentration between third trimester of pregnancy (3rdT) and postpartum (PP) period. Additionally, we will evaluate whether FMD correlates with nitrite concentration in both periods. Methods. Eligibility criteria was healthy women with singleton pregnancy, gestational age >28 weeks, nonsmokers, and no personal or family history of vascular disease. Each women was examined during 3rdT and between 8 and 12 weeks PP to evaluate FMD and nitrite concentration in whole blood. Women not examined in both periods were excluded. Values between both periods were compared using paired t tests. Correlation between FMD and nitrite was examined by Pearson correlation coefficient. Significance level set as p<0.05. Results. We invited 42 pregnant women. Among them, 35 were eligible and 7 of them were excluded for not attending the PP evaluation resulting in 28 participants analyzed. We found no significant change in FMD (10.39±5.57% vs. 8.42±4.21%; p=0.11; 3rdT vs. PP, respectively) and no significant change in nitrite concentration (257.41±122.95nmol/L vs. 237.16±90.01nmol/L; p=0.28). Baseline brachial artery diameter had a significant reduction (3.11±0.30 to 2.75±0.34mm; p<0.01). No significant correlation between FMD and nitrite during 3rdT (r=-0.13; p=0.50) or PP (r=0.14; p=0.48) was found. Conclusions. We did not observe significant changes in both FMD and nitrite concentration between third trimester and the PP period. FMD did not correlate with nitrite in both periods. More studies are needed to confirm our findings. © Informa Healthcare USA, Inc.en
dc.subjectPostpartum period-
dc.subjectartery diameter-
dc.subjectartery dilatation-
dc.subjectbrachial artery-
dc.subjectflow mediated dilation-
dc.subjectgestational age-
dc.subjecthuman experiment-
dc.subjectnormal human-
dc.subjectpregnant woman-
dc.subjectthird trimester pregnancy-
dc.titleMaternal flow-mediated dilation and nitrite concentration during third trimester of pregnancy and postpartum perioden
dc.contributor.institutionUniversidade de São Paulo (USP)-
dc.contributor.institutionEscola de Ultra-sonografia e Reciclagem Medica de Ribeirao Preto (EURP)-
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationDepartamento de Ginecologia e Obstetricia da Faculdade de Medicina de Ribeirao Preto Universidade de Sao Paulo (FMRP-USP), Av. Bandeirantes, 3900, 8 andar., 14049-900 Ribeirao Preto, Sao Paulo-
dc.description.affiliationEscola de Ultra-sonografia e Reciclagem Medica de Ribeirao Preto (EURP), Ribeirao Preto-
dc.description.affiliationDepartmento de Farmacologia da Faculdade Ciencias Medicas da Universidade Estadual de Campinas, Campinas-
dc.description.affiliationDepartment of Pharmacology Institute of Biosciences Universidade Estadual Paulista (UNESP), Botucatu-
dc.description.affiliationDepartamento de Farmacologia da Faculdade de Medicina de Ribeirao Preto Universidade de Sao Paulo (FMRP-USP), Ribeirao Preto-
dc.description.affiliationUnespDepartment of Pharmacology Institute of Biosciences Universidade Estadual Paulista (UNESP), Botucatu-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofHypertension in Pregnancy-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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