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dc.contributor.authorPepato, Maria Teresa-
dc.contributor.authorKeller, E. H.-
dc.contributor.authorBaviera, Amanda Martins-
dc.contributor.authorKettelhut, I. C.-
dc.contributor.authorVendramini, Regina Célia-
dc.contributor.authorBrunetti, Iguatemy Lourenço-
dc.date.accessioned2014-05-20T13:24:32Z-
dc.date.accessioned2016-10-25T16:45:16Z-
dc.date.available2014-05-20T13:24:32Z-
dc.date.available2016-10-25T16:45:16Z-
dc.date.issued2002-07-01-
dc.identifierhttp://dx.doi.org/10.1016/S0378-8741(02)00075-2-
dc.identifier.citationJournal of Ethnopharmacology. Clare: Elsevier Sci Ireland Ltd, v. 81, n. 2, p. 191-197, 2002.-
dc.identifier.issn0378-8741-
dc.identifier.urihttp://hdl.handle.net/11449/7642-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/7642-
dc.description.abstractThe effects of using Bauhinia forficata leaf decoction (150 g leaf/l water; 35.2+/-7.8 ml/100 g body weight mean daily dose) as a drinking-water substitute for about I month on streptozotocin-diabetes (STZ-diabetes) in male Wistar rats were investigated. The physico-metabolic parameters measured were: body weight, food and liquid intake, urinary volume, hepatic glycogen, serum triglycerides and cholesterol, plasma glucose, urinary glucose and urea, and the weight of epididymal and retroperitoneal adipose tissue and soleus and extensor digitorum longus muscles. The STZ-diabetic rats treated with decoction showed a significant reduction in serum and urinary glucose and urinary urea as compared to the STZ-diabetic control, no difference being seen between decoction-treated and -untreated non-diabetic rats. The other physico-metabolic factors showed no changes in treated STZ-diabetic rats. The improvement in carbohydrate metabolism seen in the rats treated with Bauhinia forficata decoction does not appear to be linked to the inhibition of glycogenolysis or the stimulation of glycogenesis nor does it appear to act in a way similar to insulin or the sulfonylureas, although it may act by the inhibition of neoglycogenesis in a manner similar to that of the biguanides. (C) 2002 Elsevier B.V. Ireland Ltd. All rights reserved.en
dc.format.extent191-197-
dc.language.isoeng-
dc.publisherElsevier B.V.-
dc.sourceWeb of Science-
dc.subjectanti-diabetic activitypt
dc.subjectBauhinia forficatapt
dc.subjectanti-hyperglycemic effectpt
dc.subjectstreptozotocin-diabetic ratspt
dc.titleAnti-diabetic activity of Bauhinia forficata decoction in streptozotocin-diabetic ratsen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionUniversidade de São Paulo (USP)-
dc.description.affiliationUNESP, Fac Ciências Farmaceut Araraquara, Dept Anal Clin, Araraquara, SP, Brazil-
dc.description.affiliationUSP, Fac Med Ribeirao Preto, Dept Bioquim, Ribeirao Preto, SP, Brazil-
dc.description.affiliationUnespUNESP, Fac Ciências Farmaceut Araraquara, Dept Anal Clin, Araraquara, SP, Brazil-
dc.identifier.doi10.1016/S0378-8741(02)00075-2-
dc.identifier.wosWOS:000176715300006-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofJournal of Ethnopharmacology-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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