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DC Field | Value | Language |
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dc.contributor.author | Gomes-Filho, João Eduardo | - |
dc.contributor.author | Tobias Duarte, Paulo Carvalho | - |
dc.contributor.author | Ervolino, Edilson | - |
dc.contributor.author | Bomfim, Suely Regina Mogami | - |
dc.contributor.author | Xavier Abimussi, Caio José | - |
dc.contributor.author | Mota da Silva Santos, Ludmilla | - |
dc.contributor.author | Lodi, Carolina Simonetti | - |
dc.contributor.author | Oliveira, Sandra Helena Penha de | - |
dc.contributor.author | Dezan Júnior, Eloi | - |
dc.contributor.author | Cintra, Luciano Tavares Angelo | - |
dc.date.accessioned | 2014-05-27T11:30:45Z | - |
dc.date.accessioned | 2016-10-25T18:54:30Z | - |
dc.date.available | 2014-05-27T11:30:45Z | - |
dc.date.available | 2016-10-25T18:54:30Z | - |
dc.date.issued | 2013-09-30 | - |
dc.identifier | http://dx.doi.org/10.1016/j.joen.2013.08.023 | - |
dc.identifier.citation | Journal of Endodontics. | - |
dc.identifier.issn | 0099-2399 | - |
dc.identifier.uri | http://hdl.handle.net/11449/76661 | - |
dc.identifier.uri | http://acervodigital.unesp.br/handle/11449/76661 | - |
dc.description.abstract | Introduction: The aim of this study was to investigate the capacity of endodontic regenerative procedures combining an induced blood clot, platelet-rich plasma (PRP), and bone marrow aspirate (BMA) to regenerate dental pulp in canine closed-apex necrotic teeth. Methods: Apical periodontitis was induced in 20 upper and lower premolars of 2 dogs. After biomechanical preparation, enlargement to a #60 file, and disinfection with a triantibiotic paste for 28 days, the roots were randomly assigned to 4 treatment groups: blood clot (BC), BC + PRP gel, BC + BMA gel, and BC + BMA/PRP gel. Negative controls were also included. After a 3-month follow-up period, the animals were killed. Results: Histologic analysis showed the presence of newly formed vital tissues (connective, cement-like, and bone-like tissue) in 23 of the 32 treated roots (71.87%). There was no statistically significant difference between the treatment groups. Conclusions: New vital tissues were formed and characterized as connective, cementum-like, or bone-like, but not as pulp-like tissue; PRP and/or BMA did not improve the tissue ingrowth. © 2013 American Association of Endodontists. | en |
dc.language.iso | eng | - |
dc.source | Scopus | - |
dc.subject | Bone marrow aspirate | - |
dc.subject | necrotic teeth | - |
dc.subject | platelet-rich plasma | - |
dc.subject | regenerative endodontics | - |
dc.subject | tissue engineering | - |
dc.subject | vital tissue growth | - |
dc.title | Histologic Characterization of Engineered Tissues in the Canal Space of Closed-apex Teeth with Apical Periodontitis | en |
dc.type | outro | - |
dc.contributor.institution | Universidade Estadual Paulista (UNESP) | - |
dc.identifier.doi | 10.1016/j.joen.2013.08.023 | - |
dc.identifier.wos | WOS:000327916700014 | - |
dc.rights.accessRights | Acesso restrito | - |
dc.relation.ispartof | Journal of Endodontics | - |
dc.identifier.scopus | 2-s2.0-84884538597 | - |
Appears in Collections: | Artigos, TCCs, Teses e Dissertações da Unesp |
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