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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/7684
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dc.contributor.authorNogueira, MEI-
dc.contributor.authorPassoni, M. H.-
dc.contributor.authorBiso, F. I.-
dc.contributor.authorLongo, M. D.-
dc.contributor.authorCardoso, CRP-
dc.contributor.authordos Santos, L. C.-
dc.contributor.authorVaranda, Eliana Aparecida-
dc.date.accessioned2014-05-20T13:24:36Z-
dc.date.accessioned2016-10-25T16:45:19Z-
dc.date.available2014-05-20T13:24:36Z-
dc.date.available2016-10-25T16:45:19Z-
dc.date.issued2006-04-01-
dc.identifierhttp://dx.doi.org/10.1016/j.tiv.2005.08.012-
dc.identifier.citationToxicology In Vitro. Oxford: Pergamon-Elsevier B.V., v. 20, n. 3, p. 361-366, 2006.-
dc.identifier.issn0887-2333-
dc.identifier.urihttp://hdl.handle.net/11449/7684-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/7684-
dc.description.abstractMelcanpodium divaricatian is a member of the Asteraccae and in Brazil is known as false-calendula, its flowers being used in anti-inflammatory preparations, substituting the true calendula or marigold (Calendula officinalis L.). The flower extract was investigated for mutagenic and antimutagenic effect in the Sahnonella/microsome assay. The tested extract was not mutagenic in the strains TA100, TA98, TA97a and TA102 and decreased the mutagenicity of aflatoxin B1, benzo(a)pyrene and daunomycin. Chlorophyll and triterpenes were detected in the extract, and they might have contributed to the observed effect. Our data suggest that these medicinal plants possess cancer chemopreventive properties. (c) 2005 Elsevier Ltd. All rights reserved.en
dc.format.extent361-366-
dc.language.isoeng-
dc.publisherElsevier B.V.-
dc.sourceWeb of Science-
dc.subjectSalmonella typhimuriumpt
dc.subjectantimutagenic activitypt
dc.subjectMelampodium divaricationpt
dc.subjecttriterpenespt
dc.titleInvestigation of genotoxic and antigenotoxic activities of Melampodium divaricatum in Salmonella typhimuriumen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationUniv Estadual Paulista, UNESP, Fac Pharmaceut Sci, Dept Biol Sci, BR-14801902 Araraquara, SP, Brazil-
dc.description.affiliationUniv Estadual Paulista, UNESP, Inst Chem, BR-14801970 Araraquara, SP, Brazil-
dc.description.affiliationUnespUniv Estadual Paulista, UNESP, Fac Pharmaceut Sci, Dept Biol Sci, BR-14801902 Araraquara, SP, Brazil-
dc.description.affiliationUnespUniv Estadual Paulista, UNESP, Inst Chem, BR-14801970 Araraquara, SP, Brazil-
dc.identifier.doi10.1016/j.tiv.2005.08.012-
dc.identifier.wosWOS:000236987100014-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofToxicology in Vitro-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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