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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/76923
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dc.contributor.authorFernandes, Flávio C. Bedatty-
dc.contributor.authorGóes, Márcio S.-
dc.contributor.authorDavis, Jason J.-
dc.contributor.authorBueno, Paulo Roberto-
dc.date.accessioned2014-05-27T11:30:53Z-
dc.date.accessioned2016-10-25T18:55:08Z-
dc.date.available2014-05-27T11:30:53Z-
dc.date.available2016-10-25T18:55:08Z-
dc.date.issued2013-12-15-
dc.identifierhttp://dx.doi.org/10.1016/j.bios.2013.06.043-
dc.identifier.citationBiosensors and Bioelectronics, v. 50, p. 437-440.-
dc.identifier.issn0956-5663-
dc.identifier.issn1873-4235-
dc.identifier.urihttp://hdl.handle.net/11449/76923-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/76923-
dc.description.abstractA surface confined redox group contributes to an interfacial charging (quantifiable by redox capacitance) that can be sensitively probed by impedance derived capacitance spectroscopy. In generating mixed molecular films comprising such redox groups, together with specific recognition elements (here antibodies), this charging signal is able to sensitively transduce the recognition and binding of specific analytes. This novel transduction method, exemplified here with C-reactive protein, an important biomarker of cardiac status and general trauma, is equally applicable to any suitably prepared interfacial combination of redox reporter and receptor. The assays are label free, ultrasensitive, highly specific and accompanied by a good linear range. © 2013 Elsevier B.V.en
dc.format.extent437-440-
dc.language.isoeng-
dc.sourceScopus-
dc.subjectBiosensor-
dc.subjectCapacitance spectroscopy-
dc.subjectImmunosensors-
dc.subjectRedox capacitance-
dc.subjectC-reactive proteins-
dc.subjectInterfacial charging-
dc.subjectMolecular films-
dc.subjectSpecific recognition-
dc.subjectTransduction method-
dc.subjectUltra sensitives-
dc.subjectBiosensors-
dc.subjectCapacitance-
dc.subjectantibody-
dc.subjectC reactive protein-
dc.subjectbinding affinity-
dc.subjectbiosensor-
dc.subjectcapacitance spectroscopy-
dc.subjectcontrolled study-
dc.subjectelectric capacitance-
dc.subjectelectrode-
dc.subjectimmunosensor-
dc.subjectmolecular recognition-
dc.subjectoxidation reduction state-
dc.subjectreproducibility-
dc.subjectsensitivity and specificity-
dc.subjectspectroscopy-
dc.titleLabel free redox capacitive biosensingen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionUniversity of Oxford-
dc.description.affiliationInstituto de Química Universidade Estadual Paulista, CP 355, 14800-900 Araraquara, São Paulo-
dc.description.affiliationDepartment of Chemistry University of Oxford, South Parks Road, Oxford OX1 3QZ-
dc.description.affiliationUnespInstituto de Química Universidade Estadual Paulista, CP 355, 14800-900 Araraquara, São Paulo-
dc.identifier.doi10.1016/j.bios.2013.06.043-
dc.identifier.wosWOS:000325188200068-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofBiosensors and Bioelectronics-
dc.identifier.scopus2-s2.0-84880937473-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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