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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/7834
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dc.contributor.authorMasquio Fiorentino, Flavia Angelica-
dc.contributor.authorCorrea, Marcos Antonio-
dc.contributor.authorSalgado, Hérida Regina Nunes-
dc.date.accessioned2014-05-20T13:24:52Z-
dc.date.accessioned2016-10-25T16:45:32Z-
dc.date.available2014-05-20T13:24:52Z-
dc.date.available2016-10-25T16:45:32Z-
dc.date.issued2010-01-01-
dc.identifierhttp://dx.doi.org/10.1080/10408340903232020-
dc.identifier.citationCritical Reviews In Analytical Chemistry. Philadelphia: Taylor & Francis Inc, v. 40, n. 2, p. 89-101, 2010.-
dc.identifier.issn1040-8347-
dc.identifier.urihttp://hdl.handle.net/11449/7834-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/7834-
dc.description.abstractChlorhexidine is a type of antiseptic belonging to biguanidic group and it is large, used in dentistry, human, and veterinary medicine because it is active against Gram-positive and Gram-negative microorganisms. It can be incorporated in several types of preparations and for this reason are necessary effective analytical procedures for quality control and pharmacodynamic and pharmacokinetic studies. Chlorhexidine can be analyzed by many types of assays, however the HPLC is the most used method. In this review, various methods to analyze chlorhexidine including spectrometry, chromatography, colorimetric reaction, solid phase extraction, and capillary electrophoresis are presented and the application of these methods for the determination of chlorhexidine in biological fluids and formulations are discussed.en
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.format.extent89-101-
dc.language.isoeng-
dc.publisherTaylor & Francis Inc-
dc.sourceWeb of Science-
dc.subjectreviewen
dc.subjectchlorhexidineen
dc.subjectmethods of analysisen
dc.titleAnalytical Methods for the Determination of Chlorhexidine: A Reviewen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationUNESP, Fac Ciencias Farmaceut Araraquara, Programa Posgrad Ciencias Farmaceut, BR-14801902 Araraquara, SP, Brazil-
dc.description.affiliationUNESP, Fac Ciencias Farmaceut Araraquara, Dept Farmacos & Medicamentos, BR-14801902 Araraquara, SP, Brazil-
dc.description.affiliationUnespUNESP, Fac Ciencias Farmaceut Araraquara, Programa Posgrad Ciencias Farmaceut, BR-14801902 Araraquara, SP, Brazil-
dc.description.affiliationUnespUNESP, Fac Ciencias Farmaceut Araraquara, Dept Farmacos & Medicamentos, BR-14801902 Araraquara, SP, Brazil-
dc.identifier.doi10.1080/10408340903232020-
dc.identifier.wosWOS:000277518600003-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofCritical Reviews in Analytical Chemistry-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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