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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/8135
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dc.contributor.authorGranjeiro, Erica M.-
dc.contributor.authorGomes, Felipe V.-
dc.contributor.authorAlves, Fernando H. F.-
dc.contributor.authorCrestani, Carlos Cesar-
dc.contributor.authorCorrea, Fernando M. A.-
dc.contributor.authorResstel, Leonardo B. M.-
dc.date.accessioned2014-05-20T13:25:37Z-
dc.date.available2014-05-20T13:25:37Z-
dc.date.issued2012-04-03-
dc.identifierhttp://dx.doi.org/10.1016/j.autneu.2011.11.004-
dc.identifier.citationAutonomic Neuroscience-basic & Clinical. Amsterdam: Elsevier B.V., v. 167, n. 1-2, p. 21-26, 2012.-
dc.identifier.issn1566-0702-
dc.identifier.urihttp://hdl.handle.net/11449/8135-
dc.description.abstractSeveral studies from our group have indicated that the BNST play an important role in baroreflex modulation. However, the involvement of the BNST in the chemoreflex activity is unknown. Thus, in the present study, we investigated the effect of the local bed nucleus of stria terminalis (BNST) neurotransmission inhibition by bilateral microinjections of the non-selective synaptic blocker cobalt chloride (CoCl2) on the cardiovascular responses to chemoreflex activation in rats. For this purpose, chemoreflex was activated with KCN (i.v.) before and after microinjections of CoCl2 into the BNST. Reversible BNST inactivation produced no significant changes in the magnitude and durations of both pressor and bradycardic responses to intravenous KCN infusion. These findings suggesting that BNST neurotransmission have not influence on both sympathoexcitatory and parasympathoexcitatory components of the peripheral chemoreflex activation. (C) 2012 Elsevier B.V. All rights reserved.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
dc.format.extent21-26-
dc.language.isoeng-
dc.publisherElsevier B.V.-
dc.sourceWeb of Science-
dc.subjectAutonomic nervous systemen
dc.subjectCoCl2en
dc.subjectKCNen
dc.subjectCardiovascular systemen
dc.subjectBlood pressureen
dc.subjectHeart rateen
dc.titleBed nucleus of the stria terminalis and the cardiovascular responses to chemoreflex activationen
dc.typeoutro-
dc.contributor.institutionUniversidade de São Paulo (USP)-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationUniv São Paulo, Dept Pharmacol, Sch Med Ribeirao Preto, BR-14090090 Ribeirao Preto, SP, Brazil-
dc.description.affiliationUniv São Paulo, Dept Physiol, Sch Med Ribeirao Preto, BR-14090090 Ribeirao Preto, SP, Brazil-
dc.description.affiliationSão Paulo State Univ, UNESP, Dept Nat Act Principles & Toxicol, Sch Pharmaceut Sci Araraquara, BR-14801902 Araraquara, SP, Brazil-
dc.description.affiliationUnespSão Paulo State Univ, UNESP, Dept Nat Act Principles & Toxicol, Sch Pharmaceut Sci Araraquara, BR-14801902 Araraquara, SP, Brazil-
dc.description.sponsorshipIdFAPESP: 10/17343-0-
dc.description.sponsorshipIdFAPESP: 09/03187-9-
dc.description.sponsorshipIdCNPq: 480550/2007-7-
dc.description.sponsorshipIdCNPq: 305996/2008-8-
dc.identifier.doi10.1016/j.autneu.2011.11.004-
dc.identifier.wosWOS:000301947900005-
dc.rights.accessRightsAcesso aberto-
dc.identifier.fileWOS000301947900005.pdf-
dc.relation.ispartofAutonomic Neuroscience-basic & Clinical-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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